⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11402894 | 0.86 | LMNA (0.43) | — | |
| SCHEMBL11656356 | 0.86 | LMNA (0.43) | — | |
| SCHEMBL2323889 | 0.76 | USP2 (0.34) | — | |
| SCHEMBL1198324 | 0.76 | — | — | |
| SCHEMBL6272445 | 0.76 | AKR1B1 (0.41) | — | |
| SCHEMBL37362 | 0.76 | — | — | |
| SCHEMBL97624 | 0.76 | — | — | |
| SCHEMBL22720618 | 0.76 | AKR1B1 (0.41) | — | |
| SCHEMBL22720619 | 0.76 | AKR1B1 (0.41) | — | |
| SCHEMBL574324 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017164615-A1 | METHOD FOR PREPARING 3'-AMINO-2',3'-DIDEOXYADENOSINE BY USING NUCLEOSIDE PHOSPHORYLASE DERIVED FROM BACILLUS | ST PHARM CO., LTD. (KR) | 2017-09-28 | — | — | WO | disclosed |
| US-6136601-A | ADJUSTED NUCLEOTIDE SEQUENCES WHICH CAN BE UTILIZED FOR THE GENERATION OF PREFERENTIAL MUTATION | EPOCH PHARMACEUTICALS, INC. (US) | 2000-10-24 | — | — | US | disclosed |
| US-5935830-A | SITE-DIRECTED MUTAGENESIS BY FORMING TRIPLE HELIX WITH DOUBLE-STRANDED DNA AND OLIGONUCLEOTIDE WITH ELECTROPHILIC GROUP, ELECTROPHILIC GROUP CAUSES MODIFICATION OF DNA NUCLEOTIDE, THEN REPLICATION CAUSES MUTATION | EPOCH PHARMACEUTICALS, INC. (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0021215-B1 | PSEUDOTRISACCHARIDES, THEIR PREPARATION AND USE AS MEDICAMENTS | BAYER AG (DE) | 1983-07-13 | — | — | EP | disclosed |
| US-4393051-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | disclosed |
| EP-0021215-A1 | Pseudotrisaccharides, their preparation and use as medicaments | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |