Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | TERT | O14746 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | F7 | P08709 | 3/20 | 0.48 |
| ▸ | F3 | P13726 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL25265281 | 0.78 | LMNA (0.69) | PPARGPPARDPPARAPTPN1LMNA | |
| Adipic Acid SCHEMBL30288555 | 0.78 | LMNA (0.69) | PPARGPPARDPPARAPTPN1LMNA | |
| Adipic Acid SCHEMBL28304104 | 0.78 | LMNA (0.69) | PPARGPPARDPPARAPTPN1LMNA | |
| Adipic Acid SCHEMBL28562568 | 0.78 | LMNA (0.69) | PPARGPPARDPPARAPTPN1LMNA | |
| SCHEMBL16230506 | 0.78 | PPARG (0.58) | PPARGPPARDPPARATERTPTPN1 | |
| Isopropyl Alcohol SCHEMBL29235060 | 0.76 | TSHR (0.71) | PPARGPPARDPPARAPTPN1LMNA | |
| Sebacic Acid SCHEMBL27860431 | 0.76 | TSHR (0.71) | PPARGPPARDPPARAPTPN1LMNA | |
| Octanedioate SCHEMBL28590543 | 0.76 | TSHR (0.71) | PPARGPPARDPPARAPTPN1LMNA | |
| Isopropyl Alcohol SCHEMBL29137855 | 0.76 | TSHR (0.71) | PPARGPPARDPPARAPTPN1LMNA | |
| Adipic Acid SCHEMBL27907271 | 0.76 | LMNA (0.65) | PPARGPPARDPPARAPTPN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285350-B1 | METHODS FOR THE PREPARATION OF TARGETING AGENT FUNCTIONALIZED DIBLOCK COPOLYMERS FOR USE IN FABRICATION OF THERAPEUTIC NANOPARTICLES | PFIZER (US) | 2017-11-15 | — | — | EP | disclosed |
| US-8734846-B2 | Methods for the preparation of targeting agent functionalized diblock copolymers for use in fabrication of therapeutic targeted nanoparticles | BIND BIOSCIENCES, INC. (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130115192-A1 | Methods for the Preparation of Targeting Agent Functionalized Diblock Copolymers for Use in Fabrication of Therapeutic Targeted Nanoparticles | BIND BIOSCIENCES, INC (US) | 2013-05-09 | — | — | US | disclosed |
| EP-2285350-A2 | METHODS FOR THE PREPARATION OF TARGETING AGENT FUNCTIONALIZED DIBLOCK COPOLYMERS FOR USE IN FABRICATION OF THERAPEUTIC TARGETED NANOPARTICLES | Bind Biosciences, Inc. (US) | 2011-02-23 | — | — | EP | disclosed |
| US-20100104645-A1 | METHODS FOR THE PREPARATION OF TARGETING AGENT FUNCTIONALIZED DIBLOCK COPOLYMERS FOR USE IN FABRICATION OF THERAPEUTIC TARGETED NANOPARTICLES | BIND BIOSCIENCES, INC. (US) | 2010-04-29 | — | — | US | disclosed |
| WO-2010005740-A2 | METHODS FOR THE PREPARATION OF TARGETING AGENT FUNCTIONALIZED DIBLOCK COPOLYMERS FOR USE IN FABRICATION OF THERAPEUTIC TARGETED NANOPARTICLES | BIND BIOSCIENCES, INC. (US) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130115192-A1 | Methods for the Preparation of Targeting Agent Functionalized Diblock Copolymers for Use in Fabrication of Therapeutic Targeted Nanoparticles | GNE, PAM, EPHA2 | PPARG 2246/4885PPARD 4198/4885PPARA 2574/4885 |
| US-20100104645-A1 | METHODS FOR THE PREPARATION OF TARGETING AGENT FUNCTIONALIZED DIBLOCK COPOLYMERS FOR USE IN FABRICATION OF THERAPEUTIC TARGETED NANOPARTICLES | GNE, EPHA2, PAM | PPARG 971/4885PPARD 3317/4885PPARA 1252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.