Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.47 |
| ▸ | GABRP | O00591 | 6/20 | 0.47 |
| ▸ | GABRD | O14764 | 6/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.47 |
| ▸ | GABRE | P78334 | 6/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.47 |
| ▸ | CDC7 | O00311 | 2/20 | 0.46 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127699 | 0.83 | CYP1A2 (0.53) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL930636 | 0.81 | JMJD6 (0.57) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30440953 | 0.81 | CYP1A2 (0.51) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL29466587 | 0.81 | JMJD6 (0.57) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL159881 | 0.81 | CYP1A2 (0.51) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5778009 | 0.81 | CA12 (0.51) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30234144 | 0.81 | CA12 (0.51) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL131789 | 0.81 | ALDH1A1 (0.50) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL128612 | 0.81 | CYP1A2 (0.47) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL311880 | 0.80 | CYP1A2 (0.50) | CYP1A2GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036453-A1 | Pyrrolopyridazinone Compound | CBR3, CBR1, CYC1 | CYP1A2 84/4885GABRA1 1367/4885GABRG2 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.