SCHEMBL930636

SCHEMBL930636

CCOC(=O)c1ccnc(C(=O)OCC)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JMJD6 Q6NYC1 3/20 0.57
PIK3CA P42336 1/20 0.55
CA12 O43570 3/20 0.53
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA7 P43166 3/20 0.53
CA9 Q16790 3/20 0.53
CA14 Q9ULX7 3/20 0.53
CYP1A2 P05177 2/20 0.51
JMJD7 P0C870 1/20 0.51
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HPGD P15428 1/20 0.50
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
KMT2A Q03164 1/20 0.48
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
GABRA1 P14867 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466587 1.00 JMJD6 (0.57) JMJD6PIK3CACA12CA1CA2
SCHEMBL1920448 0.90 FTO (0.61) JMJD6PIK3CACYP1A2JMJD7GABRP
SCHEMBL9297593 0.90 CYP1A2 (0.49) JMJD6PIK3CACYP1A2JMJD7NPC1
SCHEMBL16578099 0.90 KDM4E (0.61) JMJD6PIK3CACA12CA1CA2
SCHEMBL28528961 0.90 JMJD6 (0.55) JMJD6PIK3CACA12CA1CA2
SCHEMBL581406 0.89 JMJD6 (0.57) JMJD6PIK3CACA12CA1CA2
SCHEMBL8950955 0.89 MMP2 (0.48) JMJD6PIK3CACYP1A2JMJD7NPC1
SCHEMBL27459696 0.88 JMJD6 (0.50) JMJD6PIK3CACA12CA1CA2
SCHEMBL24604371 0.87 CYP1A2 (0.46) JMJD6PIK3CACA12CA1CA2
SCHEMBL8406007 0.87 JMJD6 (0.59) JMJD6PIK3CANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132575-A1 COSMETIC COMPOSITION COMPRISING NIACINAMIDE AND GINGEROL FOR THE TREATMENT OF HAIR LOSS L´OREAL (FR) 2025-06-26 WO claimed
EP-3654929-B1 AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE OREAL (FR) 2024-05-29 EP claimed
CN-115322350-A Degradable bio-based polyester and preparation method and application thereof 苏州瀚海新材料有限公司 2022-11-11 CN claimed
CN-115209862-A Composition for lightening and/or whitening keratin materials 莱雅公司 2022-10-18 CN claimed
CN-113518610-A Composition for lightening or whitening keratin materials 莱雅公司 2021-10-19 CN claimed
CN-113438938-A Composition for lightening or whitening keratin materials 莱雅公司 2021-09-24 CN claimed
EP-2953611-B1 USE OF A COMPOSITION COMPRISING AVOCADO PERSEOSE IN THE PROTECTION OF EPIDERMAL STEM CELLS EXPANSCIENCE LAB (FR) 2021-08-18 EP claimed
CN-113226253-A Composition for lightening or whitening keratin materials 莱雅公司 2021-08-06 CN claimed
US-10835468-B2 Particular pyridinedicarboxylic acid derivative/antioxidant combination L'OREAL (FR) 2020-11-17 US claimed
EP-3654929-A1 AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE L'OREAL (FR) 2020-05-27 EP claimed
WO-2014122326-A1 USE OF A COMPOSITION COMPRISING AVOCADO PERSEOSE IN THE PROTECTION OF EPIDERMAL STEM CELLS LABORATOIRES EXPANSCIENCE (FR) 2014-08-14 WO claimed
EP-1352629-B1 Use of a pyridine-dicarboxylic acid derivative or a salt thereof to stimulate or induce keratinic fiber growth and/or to prevent its loss OREAL (FR) 2011-06-22 EP claimed
US-7598278-B2 Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss L'OREAL (FR) 2009-10-06 US claimed
US-20090215837-A1 ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS L'OREAL 2009-08-27 US claimed
CN-101370776-A 5-(arylsulfonyl)-pyrazolopiperidines ELAN PHARM INC (US) 2009-02-18 CN claimed
US-20080025940-A1 Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof L'OREAL (FR) 2008-01-31 US claimed
EP-1853352-A2 USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF L'Oréal (FR) 2007-11-14 EP claimed
WO-2006079568-A2 USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF L'OREAL (FR) 2006-08-03 WO claimed
US-20030223945-A1 Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss SOCIETE L'OREAL S.A. (FR) 2003-12-04 US claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10835468-B2 Particular pyridinedicarboxylic acid derivative/antioxidant combination GPX4, PRDX3, DPYD JMJD6 607/4885PIK3CA 746/4885CA12 3725/4885
US-20030223945-A1 Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss KRT18, AKR1C3, MC1R JMJD6 1237/4885PIK3CA 2888/4885CA12 3507/4885
US-20080025940-A1 Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof KRT18, TYR, MC1R JMJD6 1985/4885PIK3CA 4474/4885CA12 1823/4885
US-20090215837-A1 ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS AKR1C3, MC1R, KRT18 JMJD6 802/4885PIK3CA 2964/4885CA12 3619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.