Styrene

Styrene

SCHEMBL1277210

C=C(C)C(=O)O.C=Cc1ccccc1.O=C1C=CC(=O)O1

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
TSHR P16473 2/20 0.45
AKR1C3 P42330 1/20 0.41
GLA P06280 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PSMD14 O00487 1/20 0.35
PTGS2 P35354 1/20 0.35
HTT P42858 1/20 0.35
HPGD P15428 1/20 0.34
CYP3A4 P08684 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
CYP2C19 P33261 1/20 0.33
AKR1C1 Q04828 1/20 0.33
AKT1 P31749 1/20 0.32
HDAC3 O15379 1/20 0.32
TNKS O95271 1/20 0.32
HDAC4 P56524 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL20573914 0.92 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL9467017 0.92 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL9482333 0.90 ALDH1A1 (0.40) ALDH1A1TSHRAKR1C3HTTCYP3A4
Styrene SCHEMBL29139874 0.89 ALDH1A1 (0.41) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL3708272 0.89 ALDH1A1 (0.47) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL27873760 0.89 ALDH1A1 (0.47) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL3361846 0.88 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL7177772 0.88 AKR1C3 (0.46) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL531225 0.88 AKR1C3 (0.46) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL27919475 0.87 ALDH1A1 (0.34) ALDH1A1TSHRAKR1C3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115490788-B Catalyst component for olefin polymerization, preparation method thereof and catalyst 中国石油化工股份有限公司 2023-10-10 CN claimed
EP-1988066-B1 Binding of fibrous material utilizing a crosslinked polyamic acid JOHNS MANVILLE (US) 2020-06-03 EP disclosed
CN-105387347-A Oil field crude oil pour point depressant and preparing method thereof CHINA NAT OFFSHORE OIL CORP 2016-03-09 CN disclosed
US-8652579-B2 Processes of making fiber-containing composites from polyamic acid-containing binder compositions JOHNS MANVILLE (US) 2014-02-18 US disclosed
US-8357746-B2 Joining fibers; formaldehyde-free; esterification of michael adduct containing hydroxyl groups and acid; cured waterproof binder ; for glass fiber insulation construction materials JOHNS MANVILLE (US) 2013-01-22 US disclosed
US-20120088032-A1 BUSINESS METHOD FOR BUILDING PERFORMANCE RETROFIT OF EXISTING SINGLE FAMILY RESIDENTIAL HOMES JOHNS MANVILLE 2012-04-12 US disclosed
US-7825214-B2 Purified styrene-maleic anhydride polymer binder JOHNS MANVILLE (US) 2010-11-02 US disclosed
EP-2083021-A1 Purified styrene-maleic anhydride polymer binder Johns Manville (US) 2009-07-29 EP disclosed
US-20090182108-A1 Purified styrene-maleic anhydride polymer binder JOHNS MANVILLE 2009-07-16 US disclosed
US-20080274292-A1 Binding of fibrous material utilizing a crosslinked polyamic acid JOHNS MANVILLE 2008-11-06 US disclosed
EP-0452010-A2 Compatibilized blends of crystalline propylene polymers and styrenic copolymers ARCO Chemical Technology, L.P. (US) 1991-10-16 EP disclosed
US-4939068-A Silane containing acid BASF AKTIENGESELLSCHAFT (DE) 1990-07-03 US disclosed
US-4935330-A Photopolymerizable mixture, photosensitive recording element containing this mixture, and the production of lithographic printing plate using this photosensitive recording element BASF AKTIENGESELLSCHAFT (DE) 1990-06-19 US disclosed
US-4816379-A Production of relief plates and printing plates by a positive-working method BASF AKTIENGESELLSCHAFT (DE) 1989-03-28 US disclosed
US-4725524-A Dry film resist and production of resist images BASF AKTIENGESELLSCHAFT (DE) 1988-02-16 US disclosed
EP-0007931-B2 RUBBER-MODIFIED TERPOLYMERS WITH IMPROVED HEAT DISTORTION RESISTANCE MONSANTO COMPANY (US) 1984-11-28 EP disclosed
US-4341695-A Rubber modified terpolymers with improved heat distortion resistance MONSANTO COMPANY (US) 1982-07-27 US disclosed
EP-0007931-B1 RUBBER-MODIFIED TERPOLYMERS WITH IMPROVED HEAT DISTORTION RESISTANCE MONSANTO COMPANY (US) 1982-05-12 EP disclosed
US-4305869-A Terpolymers with improved heat distortion resistance MONSANTO COMPANY (US) 1981-12-15 US disclosed
EP-0007931-A1 Rubber-modified terpolymers with improved heat distortion resistance MONSANTO COMPANY (US) 1980-02-20 EP disclosed