Styrene

Styrene

SCHEMBL531225

C=Cc1ccccc1.CC=C(C)C(=O)O.O=C1C=CC(=O)O1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.46
ALDH1A1 P00352 2/20 0.42
TSHR P16473 2/20 0.42
HTT P42858 1/20 0.36
MAPT P10636 1/20 0.36
GLA P06280 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
APEX1 P27695 8/20 0.34
PSMD14 O00487 1/20 0.34
PTGS2 P35354 1/20 0.34
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7177772 1.00 AKR1C3 (0.46) AKR1C3ALDH1A1TSHRHTTMAPT
Styrene SCHEMBL1830884 0.92 AKR1C3 (0.40) AKR1C3ALDH1A1TSHRHTTMAPT
Styrene SCHEMBL16618108 0.88 HTT (0.48) AKR1C3ALDH1A1TSHRHTTMAPT
Styrene SCHEMBL16618106 0.88 HTT (0.48) AKR1C3ALDH1A1TSHRHTTMAPT
Styrene SCHEMBL1277210 0.88 ALDH1A1 (0.45) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL238869 0.87 AKR1C3 (0.59) AKR1C3ALDH1A1TSHRHTTMAPT
Styrene SCHEMBL134355 0.87 AKR1C3 (0.59) AKR1C3ALDH1A1TSHRHTTMAPT
Styrene SCHEMBL9467017 0.85 ALDH1A1 (0.50) AKR1C3ALDH1A1TSHRMAPTGLA
Styrene SCHEMBL20573914 0.85 ALDH1A1 (0.50) AKR1C3ALDH1A1TSHRMAPTGLA
Styrene SCHEMBL3361846 0.85 ALDH1A1 (0.54) AKR1C3ALDH1A1TSHRMAPTGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9690027-B2 Optical film and method of preparing same LG CHEM, LTD. (KR) 2017-06-27 US disclosed
US-9261732-B2 Acryl-base polymer film, optical compensation film, and liquid-crystal display device having the same FUJIFILM CORPORATION (JP) 2016-02-16 US disclosed
US-9187633-B2 Optical film and method of manufacturing the same LG CHEM, LTD. (KR) 2015-11-17 US disclosed
US-20150085362-A1 OPTICAL FILM AND METHOD OF PREPARING SAME LG CHEM, LTD. (KR) 2015-03-26 US disclosed
US-8951643-B2 Optical film and method of preparing same LG CHEM, LTD. (KR) 2015-02-10 US disclosed
US-8911854-B2 Optical film and a production method therefor LG CHEM, LTD. (KR) 2014-12-16 US disclosed
EP-2345690-B1 OPTICAL FILM AND METHOD OF PREPARING SAME LG CHEMICAL LTD (KR) 2014-09-17 EP disclosed
US-20140239523-A1 OPTICAL FILM AND METHOD OF MANUFACTURING THE SAME LG CHEM, LTD. (KR) 2014-08-28 US disclosed
US-8758655-B2 Optical film and method of manufacturing the same LG CHEM, LTD. (KR) 2014-06-24 US disclosed
US-20140117570-A1 METHOD OF PRODUCING AN OPTICAL COMPENSATION FILM FUJIFILM CORPORATION (JP) 2014-05-01 US disclosed
EP-2345690-A2 OPTICAL FILM AND METHOD OF PREPARING SAME LG Chem, Ltd. (KR) 2011-07-20 EP disclosed
US-20110097561-A1 Optical Film and a Production Method Therefor LG CHEM LTD. (KR) 2011-04-28 US disclosed
US-20100245725-A1 ACRYL-BASE POLYMER FILM, OPTICAL COMPENSATION FILM, AND LIQUID-CRYSTAL DISPLAY DEVICE HAVING THE SAME FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
US-20100202049-A1 OPTICAL FILM AND METHOD OF MANUFACTURING THE SAME LG CHEM, LTD. 2010-08-12 US disclosed
WO-2009038342-A2 OPTICAL FILM AND METHOD OF MANUFACTURING THE SAME LG CHEM, LTD. (KR) 2009-03-26 WO disclosed
EP-1352025-A1 UREA-FORMALDEHYDE RESIN BINDERS CONTAINING STYRENE-ACRYL OR STYRENE-MALEIC ANHYDRIDE-ACRYLIC COPOLYMERS GEORGIA-PACIFIC RESINS, INC. (US) 2003-10-15 EP disclosed
WO-2002051936-A1 UREA-FORMALDEHYDE RESIN BINDERS CONTAINING STYRENE-ACRYL OR STYRENE-MALEIC ANHYDRIDE-ACRYLIC COPOLYMERS GEORGIA-PACIFIC RESINS, INC. (US) 2002-07-04 WO disclosed
US-5106696-A Thermoformable multilayer structures FERRO CORPORATION (US) 1992-04-21 US disclosed
EP-0474927-A1 Dynamically vulcanized alloys adherent to styrene copolymers and polyester compositions ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1992-03-18 EP disclosed
US-4181788-A Process for the production of thermoplastic molding materials based on vinyl polymers BAYER AKTIENGESELLSCHAFT (DE) 1980-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100245725-A1 ACRYL-BASE POLYMER FILM, OPTICAL COMPENSATION FILM, AND LIQUID-CRYSTAL DISPLAY DEVICE HAVING THE SAME CFH, RPP30, BLM AKR1C3 4310/4885ALDH1A1 3914/4885TSHR 845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.