Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 4/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | SERPINC1 | P01008 | 3/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | FGF1 | P05230 | 4/20 | 0.35 |
| ▸ | BMP2 | P12643 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
| ▸ | SHH | Q15465 | 1/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.34 |
| ▸ | FGF2 | P09038 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14846435 | 1.00 | GJB2 (0.42) | GJB2TNFF10SERPINC1SSTR1 | |
| SCHEMBL16383851 | 0.86 | SSTR1 (0.49) | GJB2TNFSSTR1SSTR2SSTR4 | |
| SCHEMBL14846437 | 0.85 | GJB2 (0.45) | GJB2TNFF10SSTR1SSTR2 | |
| SCHEMBL15171161 | 0.83 | TNF (0.41) | TNFHPSE | |
| SCHEMBL16160499 | 0.82 | SSTR1 (0.50) | GJB2TNFSSTR1SSTR2SSTR4 | |
| SCHEMBL7913970 | 0.81 | SERPINC1 (0.43) | GJB2TNFF10SERPINC1SSTR1 | |
| SCHEMBL14854492 | 0.78 | GJB2 (0.44) | GJB2TNFSSTR1SSTR2SSTR4 | |
| SCHEMBL19277305 | 0.77 | SSTR1 (0.42) | GJB2TNFSSTR1SSTR2SSTR4 | |
| SCHEMBL12000691 | 0.77 | SSTR1 (0.48) | GJB2TNFSSTR1SSTR2SSTR4 | |
| SCHEMBL16770611 | 0.77 | SSTR1 (0.54) | GJB2TNFSSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919614-B2 | Disaccharide sequences formed by uronic acid and hexose as to form polysaccharides of 8-24 monosaccharide units whose hydroxyl groups are substituted by alkyl or sulphate groups; possible to modulate activities of glycosaminoglycans type | SANOFI-AVENTIS (FR) | 2011-04-05 | — | — | US | disclosed |