Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18626562 | 0.86 | MAP4K4 (0.41) | TSHRHIF1AADRB2ADRA1ASLC2A1 | |
| SCHEMBL22434760 | 0.83 | SLC2A1 (0.42) | TSHRHIF1AADRB2ADRA1ASLC2A1 | |
| SCHEMBL17827396 | 0.79 | SLC2A1 (0.47) | SLC2A1PARP1MEN1KMT2ACYP2D6 | |
| SCHEMBL17827395 | 0.78 | KCNH2 (0.45) | TSHRHIF1AADRB2ADRA1ASLC2A1 | |
| SCHEMBL26031527 | 0.78 | SIGMAR1 (0.47) | TSHRHIF1AADRB2IDO1MEN1 | |
| SCHEMBL14438280 | 0.77 | IDO1 (0.52) | IDO1PARP1MEN1CYP1A2KMT2A | |
| SCHEMBL23008642 | 0.74 | SLC2A1 (0.38) | SLC2A1PARP1SIGMAR1EGLN2MAP4K4 | |
| SCHEMBL17480806 | 0.74 | KDM4E (0.39) | IDO1KDM4EMAPTCYP3A4 | |
| SCHEMBL12312589 | 0.74 | ALDH1A1 (0.40) | HIF1ASLC2A1PARP1CYP2D6KDM4E | |
| SCHEMBL12312577 | 0.73 | MAP4K4 (0.46) | ADRB2SLC2A1IDO1SIGMAR1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2314599-A1 | Glycopeptide antibiotic monomer derivatives | National University Corporation Nagoya University (JP) | 2011-04-27 | — | — | EP | disclosed |