Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 5/20 | 0.36 |
| ▸ | NOS1 | P29475 | 4/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | OTC | P00480 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16421611 | 1.00 | KISS1R (0.44) | KISS1RDPP7DDAH1NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL28656623 | 0.98 | KISS1R (0.43) | KISS1RDPP7DDAH1NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL28656624 | 0.98 | KISS1R (0.43) | KISS1RDPP7DDAH1NOS2NOS1 | |
| SCHEMBL22769065 | 0.94 | DPP7 (0.43) | KISS1RDPP7DDAH1NOS2NOS1 | |
| SCHEMBL20653680 | 0.94 | DPP7 (0.43) | KISS1RDPP7DDAH1NOS2NOS1 | |
| SCHEMBL13456304 | 0.94 | DPP7 (0.43) | KISS1RDPP7DDAH1NOS2NOS1 | |
| SCHEMBL14288769 | 0.86 | — | — | |
| SCHEMBL10045772 | 0.83 | GSR (0.54) | DDAH1NOS2NOS1NOS3CYP2C19 | |
| SCHEMBL31688818 | 0.83 | GSR (0.54) | DDAH1NOS2NOS1NOS3CYP2C19 | |
| SCHEMBL13776588 | 0.83 | KISS1R (0.53) | KISS1RDPP7NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048029-A1 | CYCLIC PEPTIDE SYNTHESIS | GE HEALTHCARE AS (NO) | 2011-04-28 | — | — | WO | disclosed |
| EP-1884520-A2 | Daptomycin analogs as antibacterial agents | Cubist Pharmaceuticals, Inc. (US) | 2008-02-06 | — | — | EP | disclosed |