Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.54 |
| ▸ | OTC | P00480 | 1/20 | 0.51 |
| ▸ | NOS2 | P35228 | 4/20 | 0.48 |
| ▸ | NOS3 | P29474 | 3/20 | 0.48 |
| ▸ | NOS1 | P29475 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ARG2 | P78540 | 4/20 | 0.48 |
| ▸ | ARG1 | P05089 | 3/20 | 0.48 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31688818 | 1.00 | GSR (0.54) | GSROTCNOS2NOS3NOS1 | |
| SCHEMBL3438660 | 1.00 | GSR (0.54) | GSROTCNOS2NOS3NOS1 | |
| SCHEMBL432790 | 0.94 | GSR (0.57) | GSROTCNOS2NOS3NOS1 | |
| SCHEMBL623369 | 0.94 | GSR (0.57) | GSROTCNOS2NOS3NOS1 | |
| SCHEMBL64149 | 0.94 | GSR (0.57) | GSROTCNOS2NOS3NOS1 | |
| SCHEMBL28449339 | 0.92 | GSR (0.55) | GSROTCNOS2NOS3NOS1 | |
| SCHEMBL6369985 | 0.92 | GSR (0.55) | GSROTCNOS2NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL8919761 | 0.92 | GSR (0.55) | GSRNOS2NOS3NOS1CYP2C19 | |
| SCHEMBL25670261 | 0.92 | GSR (0.55) | GSROTCNOS2NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL5971277 | 0.92 | GSR (0.55) | GSRNOS2NOS3NOS1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11872262-B2 | Means and methods for treating bacterial infections | VIB VZW (BE) | 2024-01-16 | — | — | US | disclosed |
| US-11872262-B2 | Means and methods for treating bacterial infections | VIB VZW (BE) | 2024-01-16 | — | — | US | disclosed |
| EP-3339315-B1 | ISOTOPICALLY MODIFIED COMPOUNDS AND THEIR USE AS FOOD SUPPLEMENTS | RETROTOPE INC (US) | 2023-10-18 | — | — | EP | disclosed |
| US-20210077563-A1 | Means and Methods for Treating Bacterial Infections | VIB VZW (BE) | 2021-03-18 | — | — | US | disclosed |
| US-20210040150-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS | YICHANG HUMANWELL PHARMACEUTICALS CO., LTD. (CN) | 2021-02-11 | — | — | US | disclosed |
| WO-2021026492-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS | Humanwell Pharmaceutical US (US) | 2021-02-11 | — | — | WO | disclosed |
| EP-1641888-B1 | AMINO ACID DERIVATIVES AND THEIR USE AS A SAG CONTROL AGENT | NUPLEX RESINS BV (NL) | 2012-02-29 | — | — | EP | disclosed |
| EP-2295560-A1 | Directed evolution of arginine deiminase for increased activity at physiological pH | RWTH Aachen University (DE) | 2011-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210077563-A1 | Means and Methods for Treating Bacterial Infections | VIP, MMP8, SLC11A2 | GSR 1416/4885OTC 1626/4885NOS2 209/4885 |
| US-11872262-B2 | Means and methods for treating bacterial infections | VIP, MMP8, SLC11A2 | GSR 1416/4885OTC 1626/4885NOS2 209/4885 |
| US-20210040150-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS | OPRK1, OPRL1, OPRD1 | GSR 3884/4885OTC 2544/4885NOS2 2058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.