⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13689281 | 0.74 | — | — | |
| SCHEMBL12778329 | 0.74 | CYP2C19 (0.42) | — | |
| SCHEMBL15368007 | 0.70 | ALDH1A1 (0.36) | — | |
| SCHEMBL8232105 | 0.70 | — | — | |
| SCHEMBL15367959 | 0.67 | — | — | |
| SCHEMBL10765789 | 0.67 | — | — | |
| SCHEMBL6081756 | 0.67 | ALDH1A1 (0.42) | — | |
| SCHEMBL12853895 | 0.67 | — | — | |
| SCHEMBL3062029 | 0.65 | ALDH1A1 (0.62) | — | |
| SCHEMBL80644 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530646-B2 | Oxazolidinone derivative having 7-membered hetero ring | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2013-09-10 | — | — | US | disclosed |
| US-20110098471-A1 | OXAZOLIDINONE DERIVATIVE HAVING FUSED RING | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-04-28 | — | — | US | disclosed |
| US-20100256355-A1 | OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING | Research Foundation ITSUU Laboratory and Shionogi & Co., Ltd. | 2010-10-07 | — | — | US | disclosed |