⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8232105 | 0.78 | — | — | |
| SCHEMBL12708695 | 0.78 | — | — | |
| SCHEMBL12977329 | 0.74 | CYP2C19 (0.46) | — | |
| SCHEMBL12779201 | 0.74 | — | — | |
| SCHEMBL20942720 | 0.70 | THRB (0.31) | — | |
| SCHEMBL16449772 | 0.69 | KMT2A (0.42) | — | |
| SCHEMBL19198402 | 0.69 | CTSS (0.32) | — | |
| SCHEMBL10765789 | 0.69 | — | — | |
| SCHEMBL6081756 | 0.69 | ALDH1A1 (0.42) | — | |
| SCHEMBL12045990 | 0.68 | ALDH1A1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240024497-A1 | METHODS FOR THE SYNTHESIS OF PROTEIN-DRUG CONJUGATES | CIDARA THERAPEUTICS, INC. | 2024-01-25 | — | — | US | disclosed |
| WO-2023144379-A1 | HIGH-AFFINITY LIGANDS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| US-11319300-B2 | Polyfluoro-substituted aromatic heterocyclic derivative, pharmaceutical composition containing same, and applications thereof | GUANGZHOU LIXIN PHARMACEUTICAL CO., LTD. (CN) | 2022-05-03 | — | — | US | disclosed |
| US-20210220478-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2021-07-22 | — | — | US | disclosed |
| EP-3414238-B1 | SUBSTITUTED IMIDAZOLYL-CARBOXAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-03-24 | — | — | EP | disclosed |
| US-20200397914-A1 | BENZODIAZEPINE DERIVATIVES | IMMUNOGEN, INC. | 2020-12-24 | — | — | US | disclosed |
| US-20200165229-A1 | POLYFLUORO-SUBSTITUTED AROMATIC HETEROCYCLIC DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND APPLICATIONS THEREOF | GUANGZHOU LIXIN PHARMACEUTICAL CO., LTD. (CN) | 2020-05-28 | — | — | US | disclosed |
| US-10654845-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-05-19 | — | — | US | disclosed |
| US-10349657-B2 | Substituted imidazolylcarboxamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-16 | — | — | US | disclosed |
| US-20190045783-A1 | SUBSTITUTED IMIDAZOLYLCARBOXAMIDES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-14 | — | — | US | disclosed |
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2016-12-08 | — | — | US | disclosed |
| US-9439436-B2 | Use of aryl carbamates in agriculture and other plant-related areas | NORTH CAROLINA STATE UNIVERSITY (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150327552-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2015-11-19 | — | — | US | disclosed |
| US-9125408-B2 | Use of aryl carbamates in agriculture and other plant-related areas | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-08 | — | — | US | disclosed |
| US-8884022-B2 | Inhibition of bacterial biofilms with aryl carbamates | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-11-11 | — | — | US | disclosed |
| US-20130295261-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2013-11-07 | — | — | US | disclosed |
| US-20130172187-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | NORTH CAROLINA STATE UNIVERSITY | 2013-07-04 | — | — | US | disclosed |
| US-20130123225-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY | 2013-05-16 | — | — | US | disclosed |
| US-8420145-B2 | Isosorbide derivatives and their use as flavor modifiers, tastants, and taste enhancers | SENOMYX, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-20090220662-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. | 2009-09-03 | — | — | US | disclosed |