SCHEMBL1278014

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1278012	1.00	PDE3B (0.34)	PDE3BPDE3AEHMT2TTKADORA3
	SCHEMBL1277571	0.93	FGFR1 (0.34)	EHMT2TTKTBK1
	SCHEMBL1277569	0.93	FGFR1 (0.34)	EHMT2TTKTBK1
	SCHEMBL1277241	0.90	RORC (0.32)	PDE3BPDE3A
	SCHEMBL1277237	0.90	RORC (0.32)	PDE3BPDE3A
	SCHEMBL1278142	0.90	LTA4H (0.34)	PDE3BPDE3ATTKLTA4H
	SCHEMBL1278139	0.90	LTA4H (0.34)	PDE3BPDE3ATTKLTA4H
	SCHEMBL3029283	0.90	KCNH2 (0.34)	EHMT2TBK1
	SCHEMBL3029288	0.90	KCNH2 (0.34)	EHMT2TBK1
	SCHEMBL1277954	0.88	RORC (0.32)	PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.