Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19935722 | 0.81 | MAPT (0.45) | TRPA1NPC1RAB9ATP53TDP1 | |
| SCHEMBL1449020 | 0.78 | CA3 (0.45) | NPC1RAB9ATDP1LMNAALDH1A1 | |
| SCHEMBL1449017 | 0.78 | CA3 (0.45) | NPC1RAB9ATDP1LMNAALDH1A1 | |
| SCHEMBL1449019 | 0.78 | CA3 (0.45) | NPC1RAB9ATDP1LMNAALDH1A1 | |
| SCHEMBL19449734 | 0.78 | CPS1 (0.36) | TRPA1NPC1RAB9ATP53TDP1 | |
| SCHEMBL24080246 | 0.77 | MEN1 (0.43) | NPC1RAB9ATP53TDP1LMNA | |
| SCHEMBL1448345 | 0.75 | ESR1 (0.35) | NPC1TDP1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL1448342 | 0.75 | ESR1 (0.35) | NPC1TDP1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL1448346 | 0.75 | ESR1 (0.35) | NPC1TDP1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL1448167 | 0.75 | MAPK1 (0.62) | NPC1RAB9ATDP1LMNACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8547625-B2 | Photochromic optical articles prepared with reversible thermochromic materials | TRANSITIONS OPTICAL, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20110051223-A1 | PHOTOCHROMIC OPTICAL ARTICLES PREPARED WITH REVERSIBLE THERMOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (FL) | 2011-03-03 | — | — | US | disclosed |