Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | HTR7 | P34969 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.44 |
| ▸ | TUBB | P07437 | 5/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254087 | 0.91 | ROCK1 (0.44) | HTR1AHTR7ROCK1SRCTUBB4A | |
| SCHEMBL12782554 | 0.90 | HTR1A (0.44) | HTR1AHTR7POLBKMT2AMEN1 | |
| SCHEMBL254565 | 0.89 | HTR1A (0.45) | HTR1AHTR7POLBKMT2AMEN1 | |
| SCHEMBL254431 | 0.89 | ROCK1 (0.46) | HTR1AHTR7ROCK1SRCTUBB4A | |
| SCHEMBL255202 | 0.89 | TUBB4A (0.51) | HTR1AHTR7SRCTUBB4ATUBB | |
| SCHEMBL254411 | 0.88 | ROCK1 (0.44) | HTR1AHTR7ROCK1SRCTUBB4A | |
| SCHEMBL12782570 | 0.88 | HTR1A (0.47) | HTR1AHTR7POLBKMT2AMEN1 | |
| SCHEMBL12782574 | 0.87 | ROCK1 (0.43) | HTR1AHTR7ROCK1SRCTUBB4A | |
| SCHEMBL12782559 | 0.85 | HTR1A (0.48) | HTR1AHTR7POLBKMT2AMEN1 | |
| SCHEMBL253924 | 0.85 | SRC (0.57) | HTR1AHTR7ROCK1SRCTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065705-A1 | Compositions and Methods of Treating Cell Proliferation Disorders | SAGARD HEALTHCARE ROYALTY PARTNERS, LP, AS ADMINISTRATIVE AGENT (CA) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065705-A1 | Compositions and Methods of Treating Cell Proliferation Disorders | MKI67, CCNC, CCNA1 | HTR1A 3859/4885HTR7 4007/4885POLB 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.