Sugi Predict

Sugi Predict / Compounds / SCHEMBL1278377

SCHEMBL1278377

SCHEMBL1278377

CCCCCC(CO)CC(C)=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.61
▸ ALDH1A1 P00352 1/20 0.50
▸ GPR84 Q9NQS5 7/20 0.42
▸ CA1 P00915 2/20 0.41
▸ FFAR1 O14842 1/20 0.41
▸ MAPT P10636 2/20 0.39
▸ LCK P06239 1/20 0.39
▸ PPARD Q03181 1/20 0.39
▸ ZDHHC20 Q5W0Z9 1/20 0.39
▸ ZDHHC2 Q9UIJ5 1/20 0.39
▸ CYP2D6 P10635 2/20 0.38
▸ SPHK1 Q9NYA1 1/20 0.38
▸ GMNN O75496 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ THPO P40225 1/20 0.38
▸ MTOR P42345 1/20 0.38
▸ BLM P54132 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ TP53 P04637 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL184422 0.98 LMNA (0.65) LMNAALDH1A1GPR84FFAR1MAPT
SCHEMBL10808756 0.98 LMNA (0.65) LMNAALDH1A1GPR84FFAR1MAPT
SCHEMBL9365266 0.89 LMNA (0.50) LMNAGPR84CA1FFAR1MAPT
SCHEMBL6274726 0.89 LMNA (0.50) LMNAGPR84CA1FFAR1MAPT
Hexane SCHEMBL4557975 0.89 LMNA (0.50) LMNAGPR84CA1FFAR1MAPT
Hexane SCHEMBL2810416 0.89 LMNA (0.50) LMNAGPR84CA1FFAR1MAPT
Hexane SCHEMBL8676368 0.89 LMNA (0.50) LMNAGPR84CA1FFAR1MAPT
Hexane SCHEMBL299439 0.89 LMNA (0.50) LMNAGPR84CA1FFAR1MAPT
SCHEMBL13678853 0.89 LMNA (0.59) LMNAALDH1A1GPR84FFAR1MAPT
SCHEMBL13678851 0.87 LMNA (0.57) LMNAALDH1A1GPR84FFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104316483-A Separation and identification method for cis-trans-isomer of beta-carotene XI AN MIYI BIOTECHNOLOGY CO LTD 2015-01-28 — — CN claimed
CN-103071134-A External preparation for treating rheumatic arthrodynia and traumatic pain and swelling and preparation method thereof GUANGXI YULIN BIGGOLDBIG PHARMACEUTICAL CO LTD 2013-05-01 — — CN claimed
US-5847238-A Processes for recovering xanthophylls from corn gluten meal CARGILL, INCORPORATED (US) 1998-12-08 — — US claimed
CN-103992255-B Method for preparing high-purity xanthophylls with calendula officinalis 云南云药医药研究有限公司 2017-01-18 — — CN disclosed
US-20150072942-A1 BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES MILLENNIUM PHARMACEUTICALS, INC. (US) 2015-03-12 — — US disclosed
CN-104316483-A Separation and identification method for cis-trans-isomer of beta-carotene XI AN MIYI BIOTECHNOLOGY CO LTD 2015-01-28 — — CN disclosed
CN-103071134-B External preparation for treating rheumatic arthrodynia and traumatic pain and swelling and preparation method thereof GUANGXI YULIN BIGGOLDBIG PHARMACEUTICAL CO LTD 2014-07-09 — — CN disclosed
US-8697149-B2 Extracts and compounds from “Tulbaghia violacea” and their use as biological plant protecting agents AGRARFORUM AG (DE) 2014-04-15 — — US disclosed
US-20130310320-A1 BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES MILLENNIUM PHARMACEUTICALS, INC. (US) 2013-11-21 — — US disclosed
CN-103071134-A External preparation for treating rheumatic arthrodynia and traumatic pain and swelling and preparation method thereof GUANGXI YULIN BIGGOLDBIG PHARMACEUTICAL CO LTD 2013-05-01 — — CN disclosed
US-8378099-B2 Boronic ester and acid compounds, synthesis and uses MILLENNIUM PHARMACUETICALS, INC. (US) 2013-02-19 — — US disclosed
EP-0987254-A1 NOVEL CYCLIC DIAMINE COMPOUNDS AND MEDICINE CONTAINING THE SAME Kowa Co., Ltd. (JP) 2000-03-22 — — EP disclosed
US-5847238-A Processes for recovering xanthophylls from corn gluten meal CARGILL, INCORPORATED (US) 1998-12-08 — — US disclosed
US-5780454-A Boronic ester and acid compounds PROSCRIPT, INC. (US) 1998-07-14 — — US disclosed
EP-0788360-A4 BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES PROSCRIPT INC (US) 1998-05-06 — — EP disclosed
EP-0788360-A1 BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES PROSCRIPT, INC. (US) 1997-08-13 — — EP disclosed
WO-1996013266-A1 BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES PROSCRIPT, INC. (US) 1996-05-09 — — WO disclosed
US-5410024-A Cellular antigrowth agent ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 1995-04-25 — — US disclosed
EP-0618221-A2 Heterocyclic inhibitors of farnesyl protein transferase BRISTOL-MYERS SQUIBB COMPANY (US) 1994-10-05 — — EP disclosed
EP-0611775-A2 Human cancer inhibitory pentapeptide amides ARIZONA BOARD OF REGENTS (US) 1994-08-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150072942-A1 BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES BCL6, BCAP31, CD79B LMNA 3434/4885ALDH1A1 3283/4885GPR84 1956/4885
US-20130310320-A1 BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES BCL6, BCAP31, CD79B LMNA 3434/4885ALDH1A1 3283/4885GPR84 1956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.