Hexane

Hexane

SCHEMBL299439

CCCCCC.CCCCCC.CCCCCC.CCCCCC.CCCCCC.CCCCCC.CCCCCC.CCCCCC(CC(C)=O)CC(C)=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
GPR84 Q9NQS5 7/20 0.47
CA1 P00915 2/20 0.45
FFAR1 O14842 2/20 0.45
MAPT P10636 1/20 0.43
LCK P06239 1/20 0.43
PPARD Q03181 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
CA2 P00918 2/20 0.42
FDPS P14324 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
ACE2 Q9BYF1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL8676368 1.00 LMNA (0.50) LMNAGPR84CA1FFAR1MAPT
Hexane SCHEMBL4557975 1.00 LMNA (0.50) LMNAGPR84CA1FFAR1MAPT
Hexane SCHEMBL2810416 1.00 LMNA (0.50) LMNAGPR84CA1FFAR1MAPT
SCHEMBL9365266 1.00 LMNA (0.50) LMNAGPR84CA1FFAR1MAPT
SCHEMBL15347870 0.98 LMNA (0.54) LMNAGPR84CA1FFAR1MAPT
SCHEMBL6274726 0.95 LMNA (0.50) LMNAGPR84CA1FFAR1MAPT
SCHEMBL17676315 0.93 LMNA (0.54) LMNAGPR84CA1FFAR1MAPT
SCHEMBL5014419 0.93 LMNA (0.54) LMNAGPR84CA1FFAR1MAPT
SCHEMBL13938058 0.93 LMNA (0.54) LMNAGPR84CA1FFAR1MAPT
SCHEMBL17676311 0.93 LMNA (0.54) LMNAGPR84CA1FFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11390437-B2 Pharmaceutical formulation GW Research Limited (GB) 2022-07-19 US disclosed
US-20210221587-A1 PHARMACEUTICAL FORMULATION GW PHARMA LIMITED (GB) 2021-07-22 US disclosed
US-10807777-B2 Pharmaceutical formulation GW PHARMA LIMITED (GB) 2020-10-20 US disclosed
US-20200102131-A1 PHARMACEUTICAL FORMULATION GW PHARMA LIMITED (GB) 2020-04-02 US disclosed
US-20190322427-A1 PHARMACEUTICAL FORMULATION GW PHARMA LIMITED (GB) 2019-10-24 US disclosed
US-20190270563-A1 PHARMACEUTICAL FORMULATION GW PHARMA LIMITED (GB) 2019-09-05 US disclosed
US-10179683-B2 Pharmaceutical formulation GW PHARMA LIMITED (GB) 2019-01-15 US disclosed
EP-3074382-B1 PELORUSIDE ANALOGS UNIV GENT (BE) 2017-11-15 EP disclosed
US-9771344-B2 Peloruside analogs UNIVERSITEIT GENT (BE) 2017-09-26 US disclosed
EP-2314284-B1 Cannabinoid liquid formulations for mucosal administration GW PHARMA LTD (GB) 2017-02-15 EP disclosed
US-6946150-B2 Lipophilic medicament, a solvent and a co-solvent in an amount > 55% wt/wt of the formulation; free from self emulsifying agent and/or a fluorinated propellant; cannabinoids administered by a pump action spray GW PHARMA LIMITED (GB) 2005-09-20 US disclosed
EP-1542657-A1 CANNABINOID LIQUID FORMULATIONS FOR MUCOSAL AMDINISTRATION GW Pharma Limited (GB) 2005-06-22 EP disclosed
WO-2004016246-A1 CANNABINOID LIQUID FORMULATIONS FOR MUCOSAL AMDINISTRATION GW PHARMA LIMITED (GB) 2004-02-26 WO disclosed
US-20040034108-A1 Lipophilic medicament, a solvent and a co-solvent in an amount > 55% wt/wt of the formulation; free from self emulsifying agent and/or a fluorinated propellant; cannabinoids administered by a pump action spray U.S. BANK NATIONAL ASSOCIATION 2004-02-19 US disclosed
EP-1087961-B1 PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME SANOFI SYNTHELABO (FR) 2002-08-14 EP disclosed
EP-1087961-A1 PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME SANOFI-SYNTHELABO (FR) 2001-04-04 EP disclosed
WO-1999065895-A1 PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME SANOFI-SYNTHELABO (FR) 1999-12-23 WO disclosed
EP-0070588-B1 METHOD OF PREPARING 1-ALPHA-HYDROXYVITAMIN D AND 1-ALPHA-HYDROXY-PREVITAMIN D COMPOUNDS, AND ADDUCT OF A PREVITAMIN D OR TACHYSTEROL COMPOUND WITH A SUITABLE DIENOPHILE DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1986-05-07 EP disclosed
US-4539153-A Method of preparing 1 α-hydroxyvitamin D and 1 α-hydroxyprevitamin D compounds, and adducts of a previtamin D or tachysterol compound with a suitable dienophile DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1985-09-03 US disclosed
EP-0070588-A1 Method of preparing 1-alpha-hydroxyvitamin D and 1-alpha-hydroxy-previtamin D compounds, and adduct of a previtamin D or tachysterol compound with a suitable dienophile DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1983-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040034108-A1 Lipophilic medicament, a solvent and a co-solvent in an amount > 55% wt/wt of the formulation; free from self emulsifying agent and/or a fluorinated propellant; cannabinoids administered by a pump action spray CNR1, CNR2, FAAH LMNA 1712/4885GPR84 208/4885CA1 3465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.