SCHEMBL1278627

SCHEMBL1278627

CCCN=NNc1ccc(C)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.40
NPC1 O15118 5/20 0.38
RAB9A P51151 5/20 0.38
ALDH1A1 P00352 5/20 0.38
HPGD P15428 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 7/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
KYAT1 Q16773 1/20 0.37
NPSR1 Q6W5P4 2/20 0.36
GFER P55789 2/20 0.36
POLB P06746 1/20 0.35
HTT P42858 2/20 0.35
DHODH Q02127 1/20 0.34
SCN5A Q14524 1/20 0.34
SCN2A Q99250 1/20 0.34
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10840042 1.00 MAPT (0.40) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL1278625 1.00 MAPT (0.40) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL7343923 0.90 SCN5A (0.40) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL1887617 0.90 SCN5A (0.40) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL1278598 0.83 MAPT (0.43) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL1278595 0.83 MAPT (0.43) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL10360876 0.83 MAPT (0.43) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL9655165 0.80 SCN5A (0.34) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL9655167 0.80 SCN5A (0.34) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL11147946 0.76 HTT (0.50) MAPTNPC1RAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115521243-A Tri-functionality cross-linking agent and preparation method and application thereof 波米科技有限公司 2022-12-27 CN claimed
WO-2025094596-A1 CHARGE-TRANSPORTING COMPOSITION 日産化学株式会社 2025-05-08 WO disclosed
CN-118638121-A Compounds for liquid crystal aligning agents 日产化学株式会社 2024-09-13 CN disclosed
CN-113454526-B Liquid crystal aligning agent and liquid crystal display element using same 日产化学株式会社 2024-06-21 CN disclosed
WO-2024090362-A1 CHARGE-TRANSPORTING COMPOSITION 日産化学株式会社 2024-05-02 WO disclosed
CN-115521243-B Trifunctional crosslinking agent and preparation method and application thereof 波米科技有限公司 2023-08-18 CN disclosed
CN-115584267-B Liquid crystal aligning agent and application thereof 波米科技有限公司 2023-08-04 CN disclosed
CN-111344630-B Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2023-04-04 CN disclosed
CN-111263913-B Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2023-03-28 CN disclosed
CN-111279255-B Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2023-03-14 CN disclosed
US-4319027-A Process for the manufacture of ceohem enol derivatives CIBA-GEIGY CORPORATION (US) 1982-03-09 US disclosed
US-4313945-A 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping CIBA-GEIGY CORPORATION (US) 1982-02-02 US disclosed
US-4301278-A BY HYDROGENATION IN THE PRESENCE OF A CATALYST CIBA-GEIGY CORPORATION (US) 1981-11-17 US disclosed
US-4293462-A Process for the manufacture of enol derivatives, and intermediates CIBA-GEIGY CORPORATION (US) 1981-10-06 US disclosed
US-4256739-A 7β-Amino-3-thio-3-cephem-4-carboxylic acid compounds, and antibacterial compositions and methods using them CIBA-GEIGY CORPORATION (US) 1981-03-17 US disclosed
US-4255328-A CEPHALOSPORINS CIBA-GEIGY CORPORATION (US) 1981-03-10 US disclosed
EP-0016296-A1 Cephalosporin derivatives, process for their preparation, compositions containing them, and intermediates and their preparation CIBA-GEIGY AG (CH) 1980-10-01 EP disclosed
US-4154934-A ENZYME INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1979-05-15 US disclosed
US-4110533-A PROCESS FOR THE MANUFACTURE OF ENOL DERIVATIVES CIBA-GEIGY CORPORATION (US) 1978-08-29 US disclosed
US-4073902-A ANTIMICROBIAL COMPOUNDS CIBA-GEIGY CORPORATION (US) 1978-02-14 US disclosed