Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.32 |
| ▸ | NPC1 | O15118 | 6/20 | 0.32 |
| ▸ | RAB9A | P51151 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655165 | 1.00 | SCN5A (0.34) | SCN5ASCN2AKYAT1MAPTNPC1 | |
| SCHEMBL1887617 | 0.85 | SCN5A (0.40) | SCN5ASCN2AKYAT1MAPTNPC1 | |
| SCHEMBL7343923 | 0.85 | SCN5A (0.40) | SCN5ASCN2AKYAT1MAPTNPC1 | |
| SCHEMBL1278627 | 0.80 | MAPT (0.40) | SCN5ASCN2AKYAT1MAPTNPC1 | |
| SCHEMBL1278625 | 0.80 | MAPT (0.40) | SCN5ASCN2AKYAT1MAPTNPC1 | |
| SCHEMBL10840042 | 0.80 | MAPT (0.40) | SCN5ASCN2AKYAT1MAPTNPC1 | |
| SCHEMBL9656203 | 0.78 | METAP2 (0.33) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9656197 | 0.78 | METAP2 (0.33) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9655492 | 0.77 | HTT (0.38) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9655498 | 0.77 | HTT (0.38) | MAPTNPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099016-A | Mitomycin analogs containing 7-alkoxy groups and disulfides as antibiotics | BRISTOL-MYERS COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5097036-A | Mitomycin analogs; antibiotics antitumor agents | BRISTOL-MYERS COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| US-4927943-A | ANTITUMOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| US-4814445-A | ETHERIFICATION, ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1989-03-21 | — | — | US | disclosed |