Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1278643

N.N.O=S(=O)(O)Oc1ccccc1OS(=O)(=O)O

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.52
FABP1 P07148 1/20 0.47
CA5A P35218 1/20 0.41
ELANE P08246 1/20 0.40
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
HSD11B1 P28845 1/20 0.34
HSD17B3 P37058 1/20 0.34
MAPT P10636 1/20 0.34
CHEK1 O14757 1/20 0.34
NFE2L2 Q16236 2/20 0.33
ACP1 P24666 1/20 0.33
HTR6 P50406 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL514247 0.97 SLC22A6 (0.53) SLC22A6FABP1CA5AELANETSHR
SCHEMBL1882763 0.95 SLC22A6 (0.52) SLC22A6FABP1CA5AELANETSHR
SCHEMBL28288293 0.95 SLC22A6 (0.52) SLC22A6FABP1CA5AELANETSHR
Ammonia Solution, Strong SCHEMBL11405643 0.86 HSD11B1 (0.49) SLC22A6FABP1CA5AELANETSHR
SCHEMBL560230 0.86 CA1 (0.56) SLC22A6FABP1CA5ATSHRSMN1; SMN2
Ammonia Solution, Strong SCHEMBL28878776 0.84 SLC22A6 (0.44) SLC22A6FABP1TSHRSMN1; SMN2ALDH1A1
Potassium SCHEMBL4629084 0.84 CA1 (0.54) SLC22A6FABP1CA5ATSHRSMN1; SMN2
SCHEMBL235067 0.83 HSD11B1 (0.50) SLC22A6FABP1CA5AELANETSHR
SCHEMBL3827901 0.83 SLC22A6 (0.47) SLC22A6FABP1CA5AELANETSHR
SCHEMBL29382842 0.83 HSD11B1 (0.50) SLC22A6FABP1CA5AELANETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2444492-A9 CHICKEN-DERIVED ANTI-LOX-1 ANTIBODY Hiroshima Bio-medical Co., Ltd. (JP) 2012-07-25 EP disclosed
EP-2444492-A1 CHICKEN-DERIVED ANTI-LOX-1 ANTIBODY Hiroshima Bio-medical Co., Ltd. (JP) 2012-04-25 EP disclosed
US-20120087926-A1 CHICKEN-DERIVED ANTI-LOX-1 ANTIBODY BASF COATINGS GMBH (DE) 2012-04-12 US disclosed
WO-2010147171-A1 CHICKEN-DERIVED ANTI-LOX-1 ANTIBODY 株式会社広島バイオメディカル (JP) 2010-12-23 WO disclosed