Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | FABP1 | P07148 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235067 | 0.98 | HSD11B1 (0.50) | HSD11B1HSD17B3CA1CA2TP53 | |
| SCHEMBL29382842 | 0.98 | HSD11B1 (0.50) | HSD11B1HSD17B3CA1CA2TP53 | |
| SCHEMBL9541027 | 0.96 | HSD11B1 (0.49) | HSD11B1HSD17B3CA1CA2TP53 | |
| SCHEMBL10535944 | 0.87 | HSD11B1 (0.43) | HSD11B1HSD17B3CA1CA2TP53 | |
| Ammonia Solution, Strong SCHEMBL1278643 | 0.86 | SLC22A6 (0.52) | HSD11B1HSD17B3CA1CA2TSHR | |
| SCHEMBL514247 | 0.84 | SLC22A6 (0.53) | HSD11B1HSD17B3CA1CA2TSHR | |
| SCHEMBL1879537 | 0.83 | LMNA (0.50) | HSD11B1HSD17B3CA1CA2TP53 | |
| SCHEMBL28100659 | 0.82 | HSD11B1 (0.51) | HSD11B1HSD17B3CA1CA2TP53 | |
| SCHEMBL6129400 | 0.82 | SLC22A6 (0.42) | HSD11B1HSD17B3CA1CA2TP53 | |
| SCHEMBL1882763 | 0.81 | SLC22A6 (0.52) | HSD11B1HSD17B3CA1CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4290975-A | N-Sulfonyl amine-mediated sulfamation of amines | NUTRASWEET COMPANY THE | 1981-09-22 | — | — | US | disclosed |