Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | IAPP | P10997 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404834 | 0.84 | ALDH1A1 (0.63) | GFERALDH1A1ESRRGTDP1MAOB | |
| SCHEMBL27815775 | 0.84 | GFER (0.59) | F2RL1GFERMMP12ALDH1A1TDP1 | |
| SCHEMBL4021741 | 0.83 | F2RL1 (0.53) | F2RL1MMP12ALDH1A1ALOX5OR51E2 | |
| SCHEMBL12354595 | 0.83 | F2RL1 (0.53) | F2RL1MMP12ALDH1A1ALOX5OR51E2 | |
| SCHEMBL1645396 | 0.83 | KDM4E (0.55) | F2RL1MMP12ALDH1A1ALOX5OR51E2 | |
| SCHEMBL13577768 | 0.83 | TDP1 (0.59) | F2RL1MMP12ALDH1A1ALOX5OR51E2 | |
| SCHEMBL28813051 | 0.82 | F2RL1 (0.57) | F2RL1GFERMMP12ALDH1A1ALOX5 | |
| SCHEMBL8014395 | 0.81 | IAPP (0.58) | F2RL1GFERMMP12ESRRGTDP1 | |
| SCHEMBL2206622 | 0.81 | ALDH1A1 (0.70) | F2RL1MMP12ALDH1A1ALOX5TDP1 | |
| SCHEMBL10909492 | 0.79 | TDP1 (0.59) | F2RL1GFERTDP1L3MBTL1IAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011046946-A2 | BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITORY ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS | YALE UNIVERSITY (US) | 2011-04-21 | — | — | WO | disclosed |
| EP-0870014-B9 | ALDOLASE CATALYTIC ANTIBODY | SCRIPPS RESEARCH INST (US) | 2007-10-10 | — | — | EP | disclosed |
| EP-0870014-B1 | ALDOLASE CATALYTIC ANTIBODY | SCRIPPS RESEARCH INST (US) | 2007-02-21 | — | — | EP | disclosed |