SCHEMBL12354595

SCHEMBL12354595

CC(=O)CC(=O)CCc1ccc(CO)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 1/20 0.53
MMP12 P39900 1/20 0.47
ALDH1A1 P00352 1/20 0.47
ALOX5 P09917 1/20 0.42
OR51E2 Q9H255 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 2/20 0.42
KDM6B O15054 1/20 0.42
KDM5C P41229 1/20 0.42
EGLN1 Q9GZT9 1/20 0.42
PHF8 Q9UPP1 1/20 0.42
KDM2A Q9Y2K7 1/20 0.42
POLB P06746 1/20 0.40
IAPP P10997 2/20 0.40
CYP4F2 P78329 2/20 0.40
CYP4A11 Q02928 2/20 0.40
BCHE P06276 2/20 0.39
ACHE P22303 2/20 0.39
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13577768 0.85 TDP1 (0.59) F2RL1MMP12ALDH1A1ALOX5OR51E2
SCHEMBL4021741 0.85 F2RL1 (0.53) F2RL1MMP12ALDH1A1ALOX5OR51E2
SCHEMBL1645396 0.85 KDM4E (0.55) F2RL1MMP12ALDH1A1ALOX5OR51E2
SCHEMBL8214784 0.84 ALDH1A1 (0.65) F2RL1ALDH1A1KDM4EIAPPCYP4F2
SCHEMBL12787142 0.83 F2RL1 (0.51) F2RL1MMP12ALDH1A1ALOX5OR51E2
SCHEMBL2206622 0.82 ALDH1A1 (0.70) F2RL1MMP12ALDH1A1ALOX5TDP1
SCHEMBL19520499 0.80 F2RL1 (0.83) F2RL1ALDH1A1ALOX5KDM4EPOLB
SCHEMBL363995 0.79 F2RL1 (0.47) F2RL1MMP12ALDH1A1ALOX5OR51E2
SCHEMBL12599490 0.79 PKM (0.53) F2RL1ALDH1A1ALOX5OR51E2KDM4E
SCHEMBL9404024 0.78 F2RL1 (0.46) F2RL1MMP12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8721922-B2 Printable light-emitting compositions NITTO DENKO CORPORATION (JP) 2014-05-13 US disclosed
US-8721922-B2 Printable light-emitting compositions NITTO DENKO CORPORATION (JP) 2014-05-13 US disclosed
US-20120305895-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2012-12-06 US disclosed
US-20120305895-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2012-12-06 US disclosed
US-20110193075-A1 PRINTABLE LIGHT-EMITTING COMPOSITIONS NITTO DENKO CORPORATION (JP) 2011-08-11 US disclosed
US-20110193075-A1 PRINTABLE LIGHT-EMITTING COMPOSITIONS NITTO DENKO CORPORATION (JP) 2011-08-11 US disclosed
WO-2010045263-A2 PRINTABLE LIGHT-EMITTING COMPOSITIONS NITTO DENKO CORPORATION (JP) 2010-04-22 WO disclosed
US-20090066234-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2009-03-12 US disclosed
US-20090066234-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2009-03-12 US disclosed
WO-2009006550-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2009-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090066234-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS MAP1LC3A, MAP1LC3C, CRY1 F2RL1 4767/4885MMP12 4511/4885ALDH1A1 164/4885
US-20120305895-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS ILK, CRY1, IK F2RL1 4760/4885MMP12 4553/4885ALDH1A1 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.