⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701552 | 0.80 | TSHR (0.39) | — | |
| SCHEMBL16105857 | 0.76 | TSHR (0.48) | — | |
| SCHEMBL20843914 | 0.76 | — | — | |
| SCHEMBL147208 | 0.72 | — | — | |
| SCHEMBL16487535 | 0.72 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL15939191 | 0.72 | — | — | |
| SCHEMBL21737386 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL22834733 | 0.70 | — | — | |
| SCHEMBL3490291 | 0.69 | KCNH2 (0.48) | — | |
| SCHEMBL22337568 | 0.69 | SMN1; SMN2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10448639-B2 | Fungicidal pyrazoles | FMC CORPORATION (US) | 2019-10-22 | — | — | US | disclosed |
| WO-2019059161-A1 | PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL GERMICIDE HAVING SAME AS ACTIVE INGREDIENT | 三井化学アグロ株式会社 | 2019-03-28 | — | — | WO | disclosed |
| US-9815850-B2 | Compounds, compositions and methods | DENALI THERAPEUTICS INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-20170226127-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. | 2017-08-10 | — | — | US | disclosed |
| EP-2956458-B1 | HETEROARYL-SUBSTITUTED HEXAHYDROPYRANO[3,4-D][1,3]THIAZIN-2-AMINE COMPOUNDS | PFIZER (US) | 2017-08-09 | — | — | EP | disclosed |
| CN-104220425-B | N-cycloalkyl-N-[(cycloalkenyl group phenyl) methylene]-(sulfur generation) carboxamide derivative | 拜耳知识产权有限责任公司 | 2016-10-19 | — | — | CN | disclosed |
| US-20130274099-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-17 | — | — | US | disclosed |
| EP-2029560-B1 | 1,3-OXAZOLIDIN-2-ONE DERIVATIVES USEEFUL AS CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2013-04-24 | — | — | EP | disclosed |
| EP-1572663-B1 | BIPHENYLCARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2013-03-20 | — | — | EP | disclosed |
| US-20120088662-A1 | FUNGICIDAL MIXTURES | BASF SE (DE) | 2012-04-12 | — | — | US | disclosed |
| US-20110183842-A1 | Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them | BASF SE (DE) | 2011-07-28 | — | — | US | disclosed |
| US-20110172098-A1 | Imidazole and Triazole Compounds, Their Use and Agents Containing the Same | BASF SE (DE) | 2011-07-14 | — | — | US | disclosed |
| US-20110172097-A1 | Imidazole and Triazole Compounds, Their Use and Agents Containing The Same | BASF SE (DE) | 2011-07-14 | — | — | US | disclosed |
| US-20110172096-A1 | Triazole Compounds, The Use Thereof and Preparations Containing These Compounds | BASF SE (DE) | 2011-07-14 | — | — | US | disclosed |
| US-20110172099-A1 | Imidazole and Triazole Compounds, Their Use and Agents Containing the Same | BASF SE (DE) | 2011-07-14 | — | — | US | disclosed |
| US-20110166020-A1 | Imidazole and Triazole Compounds, Use Thereof and Agents Containing Said Compounds | BASF SE (DE) | 2011-07-07 | — | — | US | disclosed |
| EP-2310360-A1 | FUNGICIDE N-CYCLOALKYL-N-BIPHENYLMETHYL-CARBOXAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2011-04-20 | — | — | EP | disclosed |
| US-7910614-B2 | Azolylmethyloxiranes, use thereof for controlling plant pathogenic fungi, and agents containing the same | BASF SE (DE) | 2011-03-22 | — | — | US | disclosed |
| US-20110055978-A1 | Pesticidal Mixtures | BASF SE (DE) | 2011-03-03 | — | — | US | disclosed |
| US-20090286681-A1 | Synergistic Fungicidal Active Compounde Combinations Containing a Carboxamide, an Azole, a Second Azole or a Strobilurin | BAYER CROPSCIENCE AG (DE) | 2009-11-19 | — | — | US | disclosed |