SCHEMBL27701552

SCHEMBL27701552

CCCCCCl.Cc1cc(F)n(C)n1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 2/20 0.39
NPC1 O15118 1/20 0.35
RECQL P46063 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
ASAH1 Q13510 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
POLB P06746 1/20 0.32
KCNH2 Q12809 3/20 0.31
LMNA P02545 1/20 0.31
TLR8 Q9NR97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1278746 0.80
SCHEMBL28027849 0.80 ALDH1A1 (0.35) TSHRALDH1A1TLR8
SCHEMBL28218621 0.72 CYP19A1 (0.45) TSHRALDH1A1NPC1RECQLRAB9A
SCHEMBL18255992 0.70 KCNH2 (0.38) KCNH2
SCHEMBL28011303 0.70 TSHR (0.39) TSHRALDH1A1KMT2AMEN1TDP1
SCHEMBL27909584 0.67 TSHR (0.60) TSHRALDH1A1NPC1RAB9ATDP1
SCHEMBL19304378 0.67 GPR84 (0.42) KMT2AMEN1ASAH1KCNH2
SCHEMBL9321144 0.65 TSHR (0.65) TSHRALDH1A1NPC1RAB9ATDP1
SCHEMBL21719851 0.64 ASAH1 (0.36) ASAH1
SCHEMBL27890170 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102300852-B Fungicide N-cycloalkyl-N-bicyclicmethylene-carboxamide derivatives BAYER CROPSCIENCE AG 2015-04-22 CN disclosed
CN-102300852-A Fungicide N-cycloalkyl-N-bicyclicmethylene-carboxamide derivatives 2011-12-28 CN disclosed
CN-101175750-B Fungicide 2-pyridyl-methylene-carboxamide derivatives BAYER CROPSCIENCE SA 2011-09-07 CN disclosed
CN-101175750-A Fungicide 2-pyridyl-methylene-carboxamide derivatives BAYER CROPSCIENCE SA (FR) 2008-05-07 CN disclosed