SCHEMBL1279129

SCHEMBL1279129

O=C(Cc1ccccc1)OC(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.57
ALDH1A1 P00352 2/20 0.55
MAPK1 P28482 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
PAM P19021 1/20 0.53
TSHR P16473 1/20 0.52
CES2 O00748 1/20 0.50
AKR1B1 P15121 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.47
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
CYP19A1 P11511 1/20 0.43
FNTA P49354 1/20 0.42
FNTB P49356 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL9357302 0.96 CES1 (0.53) CES1ALDH1A1MAPK1L3MBTL1PAM
SCHEMBL14722050 0.82 CES1 (0.50) CES1ALDH1A1MAPK1L3MBTL1PAM
SCHEMBL18304583 0.81 TDP1 (0.61) CES1ALDH1A1MAPK1TSHRSMN1; SMN2
SCHEMBL4466195 0.81 CES1 (0.57) CES1ALDH1A1MAPK1L3MBTL1PAM
SCHEMBL1346095 0.80 TSHR (0.56) CES1ALDH1A1MAPK1L3MBTL1PAM
SCHEMBL27506420 0.80 L3MBTL1 (0.55) CES1ALDH1A1MAPK1L3MBTL1PAM
SCHEMBL17633857 0.79 NAPRT (0.57) CYP19A1
SCHEMBL2833902 0.78 CES1 (0.50) CES1ALDH1A1MAPK1L3MBTL1PAM
SCHEMBL28745276 0.78 TSHR (0.47) CES1ALDH1A1MAPK1L3MBTL1TSHR
SCHEMBL28003976 0.78 HDAC1 (0.56) CES1MAPK1SMN1; SMN2KMT2AHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977814-A Compound AX-Bn with metabolic activity improving function and preparation method thereof 生命奇观(苏州)生物科技有限公司 2025-05-13 CN claimed
CN-119486565-A Perovskite precursor solution, perovskite solar cell, preparation method and photovoltaic module 天合光能股份有限公司 2025-02-18 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-111936144-B JAK inhibitors 廖细斌 2023-12-22 CN claimed
CN-115872857-A Netupitant key impurity and preparation method thereof 四川科伦药物研究院有限公司 2023-03-31 CN claimed
CN-115215879-A 3-aryl-4, 5-pyranocoumarin derivatives, and preparation method and application thereof 广西中医药大学 2022-10-21 CN claimed
CN-107565033-B Nickel oxide film and preparation method thereof, functional material, manufacturing method of film structure and electroluminescent device 浙江大学 2021-02-26 CN claimed
CN-108684983-A A kind of training algae fertilizer containing Chinese herbal medicine 金华市呗力水产养殖技术有限公司 2018-10-23 CN claimed
CN-108218753-A A kind of preparation method of 2- (4- trifluoromethyl benzyls) pyrrolidines 湖南华腾制药有限公司 2018-06-29 CN claimed
CN-104892456-A Method for preparing benzonitrile compound UNIV HUNAN 2015-09-09 CN claimed
CN-101544561-A Preparation method of trifluoromethyl phenylacetic acid UNIV JIANGSU POLYTECHNIC 2009-09-30 CN claimed
CN-1163619-C Method and compositions for determining sequence of nucleic acid molecules �Ѹ�������ѧ��˾ 2004-08-25 CN claimed
CN-1212021-A Method and compositions for determining sequence of nucleic acid molecules RAPIGENE INC (US) 1999-03-24 CN claimed
US-20250228118-A1 LIGHT-EMITTING ELEMENT AND MANUFACTURING METHOD THEREFOR, DISPLAY DEVICE, AND NICKEL OXIDE NANO-PARTICLE DISPERSION Sharp Display Technology Corporation (JP) 2025-07-10 US disclosed
CN-119977814-A Compound AX-Bn with metabolic activity improving function and preparation method thereof 生命奇观(苏州)生物科技有限公司 2025-05-13 CN disclosed
CN-119977814-A Compound AX-Bn with metabolic activity improving function and preparation method thereof 生命奇观(苏州)生物科技有限公司 2025-05-13 CN disclosed
US-5488131-A Synthesis of compounds with predetermined chirality CALIFORNIA INSTITUTE OF TECHNOLOGY 1996-01-30 US disclosed
WO-1995025714-A1 SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1995-09-28 WO disclosed
EP-0206951-B1 PROCESS FOR THE PERFLUOROALKYLATION OF AROMATIC DERIVATIVES RHONE-POULENC CHIMIE (FR) 1990-03-21 EP disclosed
EP-0206951-A2 Process for the perfluoroalkylation of aromatic derivatives RHONE-POULENC CHIMIE (FR) 1986-12-30 EP disclosed