SCHEMBL2833902

SCHEMBL2833902

C=C(Cc1ccccc1)C(=O)OC(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.50
CES2 O00748 1/20 0.44
AKR1B1 P15121 1/20 0.44
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PAM P19021 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
TSHR P16473 1/20 0.39
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
CNR2 P34972 2/20 0.37
CTBP2 P56545 1/20 0.37
EPHX2 P34913 1/20 0.37
TXNRD1 Q16881 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4976027 0.83 CES1 (0.44) CES1CES2AKR1B1ALDH1A1MAPK1
SCHEMBL4466195 0.82 CES1 (0.57) CES1CES2AKR1B1ALDH1A1MAPK1
SCHEMBL28107637 0.82 CES1 (0.42) CES1CES2AKR1B1ALDH1A1MAPK1
SCHEMBL27918597 0.80 CES1 (0.48) CES1CES2AKR1B1ALDH1A1MAPK1
SCHEMBL906378 0.80 CES1 (0.47) CES1CES2AKR1B1ALDH1A1MAPK1
SCHEMBL28582716 0.80 CES1 (0.52) CES1CES2AKR1B1ALDH1A1MAPK1
SCHEMBL15820652 0.79 TSHR (0.42) CES1CES2AKR1B1ALDH1A1MAPK1
SCHEMBL2367626 0.79 ALDH1A1 (0.49) ALDH1A1MAPK1L3MBTL1MEN1KMT2A
SCHEMBL1279129 0.78 CES1 (0.57) CES1CES2AKR1B1ALDH1A1MAPK1
SCHEMBL8767243 0.78 CES1 (0.50) CES1CES2AKR1B1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106119443-B The grease proofing antifouling care agent of aerosol type surface waterproofing 崔晓雪 2018-08-21 CN disclosed
CN-106119443-A The grease proofing antifouling nursing agent of aerosol type surface waterproofing 崔晓雪 2016-11-16 CN disclosed
EP-2092025-B1 COATINGS COMPRISING TERPENE PPG IND OHIO INC (US) 2012-08-15 EP disclosed
EP-2397525-A2 Coating comprising terpene PPG Industries Ohio, Inc. (US) 2011-12-21 EP disclosed
US-7776959-B2 Coatings comprising terpene PPG INDUSTRIES OHIO, INC. (US) 2010-08-17 US disclosed
WO-2010075173-A1 COPOLYMERS OF ALPHA-OLEFIN TYPE MONOMERS AND CURABLE FILM-FORMING COMPOSITIONS CONTAINING THEM PPG INDUSTRIES OHIO, INC. (US) 2010-07-01 WO disclosed
US-20100160561-A1 COPOLYMERS OF ALPHA-OLEFIN TYPE MONOMERS AND CURABLE FILM-FORMING COMPOSITIONS CONTAINING THEM PPG INDUSTRIES OHIO, INC. (US) 2010-06-24 US disclosed
EP-1474454-B1 THERMOSETTING COMPOSITIONS CONTAINING ALTERNATING COPOLYMERS OF ISOBUTYLENE TYPE MONOMERS PPG IND OHIO INC (US) 2009-11-18 EP disclosed
US-7619040-B2 Compositions containing copolymers of olefinic monomers PPG INDUSTRIES OHIO, INC. (US) 2009-11-17 US disclosed
US-7608676-B2 Coatings comprising the reaction product of a terpene, an acrylic monomer and a phenolic compound PPG INDUSTRIES OHIO, INC. (US) 2009-10-27 US disclosed
WO-2003070833-A2 RADIATION CURABLE COMPOSITIONS CONTAINING COPOLYMERS OF ISOBUTYLENE AND ACRYLIC MONOMERS PPG INDUSTRIES OHIO, INC. (US) 2003-08-28 WO disclosed
WO-2003070782-A1 COMPOSITIONS CONTAINING COPOLYMERS OF POST-POLYMERIZATION REACTED (METH)ACRYLATE MONOMERS PPG INDUSTRIES OHIO, INC. (US) 2003-08-28 WO disclosed
US-6586530-B1 controlled radical (co)polymerization process to produce the low surface tension (meth)acrylate containing block copolymers. PPG INDUSTRIES OHIO, INC. 2003-07-01 US disclosed
US-6583223-B2 First block is radically polymerizable fluoroalkyl(meth)acrylate monomer, second block is ethylenically unsaturated monomer that is free of hydroxyl groups and amine groups; thermosetting reactants PPG INDUSTRIES OHIO, INC. 2003-06-24 US disclosed
US-20030114593-A1 Low surface tension (meth) acrylate containing block copolymer prepared by controlled radical polymerization PPG INDUSTRIES OHIO, INC. 2003-06-19 US disclosed
US-20030100675-A1 Coating compositions which contain a low surface tension (meth) acrylate containing block copolymer flow control agent PPG INDUSTRIES OHIO, INC. 2003-05-29 US disclosed
US-20030096929-A1 Copolymers comprising low surface tension (meth) acrylates PPG INDUSTRIES OHIO, INC. 2003-05-22 US disclosed
WO-2003027159-A2 COMPOSITIONS CONTAINING A LOW SURFACE TENSION (METH)ACRYLATE CONTAINING BLOCK COPOLYMER PPG INDUSTRIES OHIO, INC. (US) 2003-04-03 WO disclosed
WO-2003027155-A1 COPOLYMERS COMPRISING LOW SURFACE TENSION (METH)ACRYLATES PPG INDUSTRIES OHIO, INC. (US) 2003-04-03 WO disclosed
US-4743667-A ACRYLATED SILOXXANES, OXYGEN PERMEABLE NIPPON CONTACT LENS, INC. (JP) 1988-05-10 US disclosed