Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16189625 | 0.91 | SMN1; SMN2 (0.66) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL128950 | 0.86 | KMT2A (0.54) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL129942 | 0.85 | CA1 (0.49) | ALDH1A1LMNAMAPTCA1CA2 | |
| SCHEMBL129920 | 0.84 | CA1 (0.50) | ALDH1A1LMNACA1CA2 | |
| SCHEMBL129917 | 0.83 | POLB (0.50) | LMNASMN1; SMN2MAPTCA1CA2 | |
| SCHEMBL5899127 | 0.81 | ALDH1A1 (0.74) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL17212230 | 0.81 | CA1 (0.60) | ALDH1A1LMNAMEN1KMT2ACA1 | |
| SCHEMBL127928 | 0.80 | CA1 (0.48) | ALDH1A1LMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6382633 | 0.80 | CA1 (0.69) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL129058 | 0.78 | THRB (0.46) | ALDH1A1SMN1; SMN2MAPTHTTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227966-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-01-05 | — | — | US | disclosed |
| US-20140315939-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-10-23 | — | — | US | disclosed |
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | ALDH1A1 2930/4885LMNA 3821/4885SMN1; SMN2 3296/4885 |
| US-20140315939-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | ALDH1A1 3376/4885LMNA 3733/4885SMN1; SMN2 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.