Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12793408 | 0.99 | KMT2A (0.57) | MEN1KMT2AGAAHPGDLMNA | |
| SCHEMBL12791638 | 0.99 | KMT2A (0.57) | MEN1KMT2AGAAHPGDLMNA | |
| SCHEMBL12792637 | 0.87 | ALDH1A1 (0.52) | MEN1KMT2AGAATSHRHTT | |
| SCHEMBL17779231 | 0.83 | MEN1 (0.56) | MEN1KMT2AGAAHPGDLMNA | |
| SCHEMBL17779290 | 0.82 | KMT2A (0.55) | MEN1KMT2AGAAHPGDLMNA | |
| SCHEMBL12082345 | 0.79 | KMT2A (0.55) | MEN1KMT2AGAAHPGDLMNA | |
| SCHEMBL15652199 | 0.78 | MEN1 (0.66) | MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL12082347 | 0.78 | KMT2A (0.54) | MEN1KMT2AGAAHPGDLMNA | |
| SCHEMBL12082338 | 0.78 | KMT2A (0.54) | MEN1KMT2AGAAHPGDLMNA | |
| SCHEMBL24745778 | 0.77 | MEN1 (0.64) | MEN1KMT2AGAAHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305633-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, USE OF THE CATECHOL DERIVATIVE AND USE OF THE PHARMACEUTICAL COMPOSITION | Kissei Pharmaceutical Co., Ltd. (JP) | 2011-04-06 | — | — | EP | disclosed |