Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.51 |
| ▸ | CPS1 | P31327 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15651833 | 0.88 | KDM4E (0.58) | MEN1KMT2ATSHRGAAPOLB | |
| SCHEMBL30630172 | 0.83 | MEN1 (0.64) | MEN1KMT2AHPGDLMNATSHR | |
| SCHEMBL24747200 | 0.83 | MEN1 (0.64) | MEN1KMT2AHPGDLMNATSHR | |
| SCHEMBL15651401 | 0.82 | HPGD (0.47) | MEN1KMT2AHPGDLMNATSHR | |
| SCHEMBL15652199 | 0.82 | MEN1 (0.66) | MEN1KMT2AGAAHTR4ALDH1A1 | |
| SCHEMBL17076761 | 0.82 | ACHE (0.47) | MEN1KMT2AHPGDLMNAGAA | |
| SCHEMBL15651429 | 0.82 | MEN1 (0.62) | MEN1KMT2AHPGDLMNATSHR | |
| SCHEMBL15651106 | 0.82 | ACHE (0.47) | MEN1KMT2AHPGDLMNAGAA | |
| SCHEMBL15651416 | 0.80 | MEN1 (0.63) | MEN1KMT2AHPGDLMNATSHR | |
| SCHEMBL24745777 | 0.80 | MEN1 (0.63) | MEN1KMT2AHPGDLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |