Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.60 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12079109 | 0.90 | NAMPT (0.77) | NAMPTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12335069 | 0.84 | NAMPT (1.00) | NAMPT | |
| SCHEMBL7674591 | 0.83 | LMNA (0.62) | NAMPTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12077744 | 0.83 | MEN1 (0.72) | NAMPTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12078116 | 0.83 | NAMPT (0.60) | NAMPTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12090287 | 0.83 | NAMPT (0.60) | NAMPTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL19358884 | 0.82 | CXCR4 (0.73) | NAMPTLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL12078481 | 0.81 | NAMPT (0.77) | NAMPTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12077395 | 0.81 | NAMPT (0.88) | NAMPTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12010884 | 0.80 | NAMPT (0.72) | NAMPTLMNASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258356-B1 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | CT INGENIERIA GENETICA BIOTECNOLOGIA (CU) | 2017-09-27 | — | — | EP | disclosed |
| US-8722742-B2 | Chemical compounds having antiviral activity against Dengue virus and other Flaviviruses | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2014-05-13 | — | — | US | disclosed |
| US-8722742-B2 | Chemical compounds having antiviral activity against Dengue virus and other Flaviviruses | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2014-05-13 | — | — | US | disclosed |
| US-20110065686-A1 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2011-03-17 | — | — | US | disclosed |
| US-20110065686-A1 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2011-03-17 | — | — | US | disclosed |
| EP-2258356-A2 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | Centro De Ingenieria Genetica Y Biotecnologia (CU) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009106019-A2 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065686-A1 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | MAVS, EIF2AK2, ZC3HAV1 | NAMPT 242/4885LMNA 1364/4885SMN1; SMN2 3418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.