SCHEMBL12794893

SCHEMBL12794893

CCO[Si](C)(CCCCN)OC

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13374204 0.94
SCHEMBL452817 0.89 DNM1 (0.36) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL6652274 0.88
SCHEMBL2927562 0.87 DNM1 (0.40) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL9699848 0.87 DNM1 (0.40) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL9698429 0.87 DNM1 (0.40) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL964814 0.87 DNM1 (0.40) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL483768 0.87 DNM1 (0.40) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL483440 0.87 DNM1 (0.40) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL9699788 0.87 DNM1 (0.40) DNM1MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7905927-B2 Method for lightening and/or coloring human keratin fibers using a composition comprising an aminotrialkoxy silane or aminotrialkenyloxy silane compound and device L'OREAL, SA (FR) 2011-03-15 US disclosed
US-20100303748-A1 METHOD FOR LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING A COMPOSITION COMPRISING AN AMINOTRIALKOXY SILANE OR AMINOTRIALKENYLOXY SILANE COMPOUND AND DEVICE L'OREAL S.A. (FR) 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100303748-A1 METHOD FOR LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING A COMPOSITION COMPRISING AN AMINOTRIALKOXY SILANE OR AMINOTRIALKENYLOXY SILANE COMPOUND AND DEVICE KRT18, FABP4, APMAP DNM1 4388/4885MEN1 4698/4885KMT2A 1543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.