SCHEMBL12795161

SCHEMBL12795161

C=CC(=O)OCCCN(C)CCCOc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LSS P48449 10/20 0.66
THRB P10828 1/20 0.56
ACHE P22303 4/20 0.53
BCHE P06276 3/20 0.53
LTA4H P09960 2/20 0.51
PPARA Q07869 2/20 0.50
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12795163 0.96 LSS (0.65) LSSTHRBACHEBCHELTA4H
SCHEMBL11994238 0.89 THRB (0.66) LSSTHRBLTA4HPPARAGAA
SCHEMBL22609158 0.89 THRB (0.66) LSSTHRBLTA4HPPARAGAA
SCHEMBL13579151 0.88 BCHE (0.59) LSSTHRBACHEBCHEPPARA
SCHEMBL15525736 0.87 THRB (0.64) LSSTHRBLTA4HPPARAGAA
SCHEMBL12795140 0.86 LSS (0.56) LSSTHRBACHEBCHELTA4H
SCHEMBL7647944 0.86 ACHE (0.53) LSSACHEBCHEGAA
SCHEMBL12795159 0.85 BCHE (0.58) LSSTHRBACHEBCHE
SCHEMBL899301 0.85 THRB (0.77) LSSTHRBLTA4HPPARAGAA
SCHEMBL12795150 0.84 LSS (0.53) LSSTHRBACHEBCHEPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2130817-B1 Polymerizable Type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2016-01-06 EP disclosed
US-8389769-B2 Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-03-05 US disclosed
US-8389769-B2 Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-03-05 US disclosed
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-17 US disclosed
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS CCNH, CRKL, ERH LSS 1831/4885THRB 3119/4885ACHE 3603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.