SCHEMBL12797648

SCHEMBL12797648

COC(=O)c1cccc(Cc2cccc(C)c2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.64
CYP4F2 P78329 2/20 0.62
CYP4A11 Q02928 2/20 0.62
SLC7A5 Q01650 1/20 0.55
MRGPRX4 Q96LA9 2/20 0.51
GPR17 Q13304 1/20 0.51
MAPT P10636 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
ALOX12 P18054 1/20 0.51
ALDH1A1 P00352 2/20 0.50
KDM4E B2RXH2 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NPC1 O15118 1/20 0.50
HIF1A Q16665 1/20 0.49
MPO P05164 1/20 0.48
FOLH1 Q04609 1/20 0.48
HPGD P15428 1/20 0.48
MAOB P27338 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8993120 0.89 MAPT (0.56) LOXL2CYP4F2CYP4A11MAPTMEN1
SCHEMBL2069334 0.87 LOXL2 (0.68) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4
SCHEMBL25464582 0.86 LOXL2 (0.59) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4
SCHEMBL25464630 0.86 LOXL2 (0.59) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4
SCHEMBL28289702 0.84 GPR17 (0.65) LOXL2CYP4F2CYP4A11GPR17MAPT
SCHEMBL40429 0.84 GPR17 (0.65) LOXL2CYP4F2CYP4A11GPR17MAPT
SCHEMBL29534771 0.84 GPR17 (0.65) LOXL2CYP4F2CYP4A11GPR17MAPT
SCHEMBL481481 0.84 CYP4F2 (0.67) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4
SCHEMBL9829957 0.83 LOXL2 (0.62) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4
SCHEMBL9938380 0.83 MRGPRX4 (0.68) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2311900-A1 Star polymer and method for producing the same Nippon Soda Co., Ltd. (JP) 2011-04-20 EP disclosed