Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.47 |
| ▸ | ERN1 | O75460 | 5/20 | 0.44 |
| ▸ | MLYCD | O95822 | 2/20 | 0.41 |
| ▸ | BRD2 | P25440 | 3/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670786 | 0.87 | MLYCD (0.39) | BRD4ERN1MLYCDBRD2CREBBP | |
| SCHEMBL1670785 | 0.87 | MLYCD (0.39) | BRD4ERN1MLYCDBRD2CREBBP | |
| SCHEMBL12800997 | 0.82 | BRD4 (0.42) | BRD4ERN1MLYCDBRD2 | |
| SCHEMBL1670399 | 0.77 | TLR8 (0.39) | BRD4ERN1MLYCDBRD2CREBBP | |
| SCHEMBL1670398 | 0.77 | TLR8 (0.39) | BRD4ERN1MLYCDBRD2CREBBP | |
| SCHEMBL12362813 | 0.72 | BRD4 (0.66) | BRD4ERN1MLYCDBRD2CREBBP | |
| SCHEMBL1670718 | 0.72 | TLR8 (0.41) | BRD4MLYCDBRD2CREBBP | |
| SCHEMBL1670714 | 0.72 | TLR8 (0.41) | BRD4MLYCDBRD2CREBBP | |
| SCHEMBL12800998 | 0.71 | BRD4 (0.45) | BRD4ERN1MLYCDBRD2CREBBP | |
| Hydrochloric Acid SCHEMBL23174957 | 0.71 | BRD4 (0.63) | BRD4ERN1MLYCDBRD2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |