Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 9/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670399 | 1.00 | TLR8 (0.39) | TLR8BRD4MLYCDCNR2ERN1 | |
| SCHEMBL1670786 | 0.90 | MLYCD (0.39) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1670785 | 0.90 | MLYCD (0.39) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1670714 | 0.83 | TLR8 (0.41) | TLR8BRD4MLYCDCNR2BRD2 | |
| SCHEMBL1670718 | 0.83 | TLR8 (0.41) | TLR8BRD4MLYCDCNR2BRD2 | |
| SCHEMBL1670720 | 0.77 | TLR8 (0.39) | TLR8BRD4CNR2HDAC3HDAC4 | |
| SCHEMBL12801012 | 0.77 | BRD4 (0.47) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1672893 | 0.75 | MLYCD (0.41) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1672895 | 0.75 | MLYCD (0.41) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1682611 | 0.73 | BRD4 (0.38) | BRD4MLYCDERN1BRD2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |