Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 12/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 12/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 12/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903453 | 0.90 | PRSS1 (0.56) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL13835502 | 0.88 | PRSS1 (0.52) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2111845 | 0.87 | PRSS1 (0.64) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL12801747 | 0.86 | PRSS1 (0.52) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2109383 | 0.86 | PRSS1 (0.64) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL13967330 | 0.85 | PRSS1 (0.55) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2110848 | 0.84 | PRSS1 (0.57) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL1668683 | 0.83 | PRSS1 (0.56) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2111114 | 0.82 | PRSS1 (0.64) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2109366 | 0.82 | PRSS1 (0.74) | PRSS1PRSS2PRSS3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295874-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-22 | — | — | US | claimed |
| US-9771345-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |
| US-9771345-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |
| US-9771345-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |
| US-20120295874-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120295874-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120295874-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295874-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | MYOF, FTH1, HCCS | PRSS1 3204/4885PRSS2 3599/4885PRSS3 4002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.