⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981790 | 0.72 | — | — | |
| Water SCHEMBL10814803 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL2526119 | 0.70 | — | — | |
| SCHEMBL15428089 | 0.70 | LMNA (0.33) | — | |
| SCHEMBL31098685 | 0.69 | LMNA (0.42) | — | |
| SCHEMBL11970846 | 0.68 | — | — | |
| SCHEMBL14830433 | 0.68 | — | — | |
| SCHEMBL15428088 | 0.66 | — | — | |
| SCHEMBL9225134 | 0.66 | CYP2A6 (0.55) | — | |
| SCHEMBL6269292 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327668-A | Enzymatic synthesis method and application of domide prodrug (S) -3-amino-2, 6-piperidinedione | 中国科学院微生物研究所 | 2024-01-02 | — | — | CN | disclosed |
| US-20180327379-A1 | 2',6'-DIOXO-3'-DEUTERO-PIPERDIN-3-YL-ISOINDOLINE COMPOUNDS | DEUTERX LLC (US) | 2018-11-15 | — | — | US | disclosed |
| US-20180118712-A1 | 2',6'-DIOXO-3'-DEUTERO-PIPERDIN-3-YL-ISOINDOLINE COMPOUNDS | DEUTERX LLC (US) | 2018-05-03 | — | — | US | disclosed |
| EP-2699091-B1 | 2',6'-DIOXO-3'-DEUTERO-PIPERDIN-3-YL-ISOINDOLINE COMPOUNDS | DEUTERX LLC (US) | 2017-06-21 | — | — | EP | disclosed |
| US-20160002202-A1 | 2',6'-DIOXO-3'-DEUTERO-PIPERDIN-3-YL-ISOINDOLINE COMPOUNDS | DEUTERIA PHARMACEUTICALS, INC. | 2016-01-07 | — | — | US | disclosed |
| US-9090585-B2 | 2,6-dioxo-3-deutero-piperdin-3-yl-isoindoline compounds | DEUTERX, LLC (US) | 2015-07-28 | — | — | US | disclosed |
| EP-2699091-A1 | 2',6'-DIOXO-3'-DEUTERO-PIPERDIN-3-YL-ISOINDOLINE COMPOUNDS | Deuterx, LLC (US) | 2014-02-26 | — | — | EP | disclosed |
| US-20120252844-A1 | 2,6-DIOXO-3-DEUTERO-PIPERDIN-3-YL-ISOINDOLINE COMPOUNDS | DEUTERIA PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | US | disclosed |
| WO-2012135299-A1 | 2',6'-DIOXO-3'-DEUTERO-PIPERDIN-3-YL-ISOINDOLINE COMPOUNDS | DEUTERIA PHARMACEUTICALS INC (US) | 2012-10-04 | — | — | WO | disclosed |