SCHEMBL31098685

SCHEMBL31098685

NC(=O)N1CCCC(=O)C1=O

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
CYP11B2 P19099 17/20 0.40
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4703841 0.81 CYP11B2 (0.40) LMNACYP11B2TSHRHSD17B10
Squamolone SCHEMBL1051735 0.79
SCHEMBL16100768 0.79 LMNA (0.43) LMNATSHR
Squamolone SCHEMBL28367081 0.77 LMNA (0.57) LMNACYP11B2TSHRHSD17B10
SCHEMBL13133032 0.74
SCHEMBL10650248 0.73
SCHEMBL4702017 0.73 LMNA (0.52) LMNACYP11B2TSHRHSD17B10
SCHEMBL1424272 0.71 LMNA (0.50) LMNACYP11B2TSHRHSD17B10
SCHEMBL6386673 0.71 TSHR (0.67) LMNATSHR
SCHEMBL5509622 0.70 LMNA (0.39) LMNACYP11B2TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120424070-A Design synthesis and application of spiro [ indoline-3, 3 '-quinoline ] -2,2' -diketopiperidine carboxamide compound 西南大学 2025-08-05 CN disclosed
CN-120424070-A Design synthesis and application of spiro [ indoline-3, 3 '-quinoline ] -2,2' -diketopiperidine carboxamide compound 西南大学 2025-08-05 CN disclosed
CN-118666840-A Design synthesis and application of spiro [ pyrrolidine-3, 3 '-quinoline ] -2,2' -diketopiperidine carboxamide compound 西南大学 2024-09-20 CN disclosed
CN-118666840-A Design synthesis and application of spiro [ pyrrolidine-3, 3 '-quinoline ] -2,2' -diketopiperidine carboxamide compound 西南大学 2024-09-20 CN disclosed