Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342438 | 0.77 | TSHR (0.34) | ALDH1A1USP2GAAPKMHPGD | |
| SCHEMBL9180441 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TSHRTP53CYP3A4TDP1 | |
| SCHEMBL30692102 | 0.74 | KDM4E (0.37) | ALDH1A1USP2GAAPKMHPGD | |
| SCHEMBL12808354 | 0.72 | USP2 (0.34) | ALDH1A1USP2GAAPKMHPGD | |
| SCHEMBL11415140 | 0.71 | TSHR (0.39) | ALDH1A1USP2GAAPKMHPGD | |
| SCHEMBL560581 | 0.71 | TSHR (0.39) | ALDH1A1USP2GAAPKMHPGD | |
| SCHEMBL9803794 | 0.71 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10TSHRTP53 | |
| SCHEMBL9181900 | 0.69 | CA1 (0.31) | ALDH1A1GAA | |
| SCHEMBL31510796 | 0.68 | ALDH1A1 (0.33) | ALDH1A1ALOX15HSD17B10TSHRTP53 | |
| SCHEMBL8764562 | 0.68 | ALDH1A1 (0.32) | ALDH1A1TSHRTP53CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142586-B1 | SEALANT COMPOSITION COMPRISING POLYTHIOETHER | PRC DESOTO INT INC (US) | 2011-04-06 | — | — | EP | disclosed |