SCHEMBL560581

SCHEMBL560581

CCC(C)c1cc(C(C)CC)c(N)c(C)c1N

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
USP2 O75604 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
PKM P14618 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
RORC P51449 1/20 0.36
AR P10275 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12808354 0.83 USP2 (0.34) TSHRUSP2ALDH1A1GAAPKM
SCHEMBL11415140 0.82 TSHR (0.39) TSHRUSP2ALDH1A1GAAPKM
SCHEMBL5575900 0.80 TSHR (0.30) TSHR
SCHEMBL10341252 0.78 ALDH1A1 (0.33) TSHRUSP2ALDH1A1GAAPKM
SCHEMBL11683236 0.77 TSHR (0.50) TSHRUSP2ALDH1A1GAAPKM
SCHEMBL4549115 0.77 TSHR (0.35) TSHRUSP2ALDH1A1GAAPKM
SCHEMBL30692102 0.77 KDM4E (0.37) TSHRUSP2ALDH1A1GAAPKM
SCHEMBL116802 0.76 AR (0.44) TSHRUSP2ALDH1A1GAAPKM
SCHEMBL342170 0.76 TSHR (0.38) TSHRUSP2ALDH1A1GAAPKM
SCHEMBL740098 0.75 POLB (0.38) TSHRALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3938416-B1 POLYURETHANE COATING COMPOSITIONS AND THEIR USE AS GEL COATS COVESTRO LLC (US) 2025-09-10 EP disclosed
US-20240376246-A1 ONE-POT PROCESS FOR THE PRODUCTION OF POLYCARBODIIMIDE CURED POLYMERS BASF SE (DE) 2024-11-14 US disclosed
US-20240343941-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2024-10-17 US disclosed
EP-4402191-A1 ONE-POT PROCESS FOR THE PRODUCTION OF POLYCARBODIIMIDE CURED POLYMERS BASF SE (DE) 2024-07-24 EP disclosed
EP-4380990-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2024-06-12 EP disclosed
CN-117980366-A One pot process for producing polycarbodiimide cured polymers 巴斯夫欧洲公司 2024-05-03 CN disclosed
CN-117836344-A Dual cure resin composition comprising uretdione containing compounds and use thereof in 3D printing 巴斯夫欧洲公司 2024-04-05 CN disclosed
WO-2023041443-A1 ONE-POT PROCESS FOR THE PRODUCTION OF POLYCARBODIIMIDE CURED POLYMERS BASF SE (DE) 2023-03-23 WO disclosed
WO-2023012000-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2023-02-09 WO disclosed
US-11566145-B2 Polyurethane coating compositions and their use as gel coats COVESTRO LLC (US) 2023-01-31 US disclosed
US-6530849-B2 Copolymer of toluene-2,4- or 2,6-diisocyanate, low molecular weight polyoxypropylene glycol and diamine functional chain extender; high resilience and shear resistance UNIROYAL CHEMICAL COMPANY, INC. 2003-03-11 US disclosed
WO-2002064658-A1 LOW COST, RESILIENT, SHEAR RESISTANT POLYURETHANE ELASTOMERS FOR GOLF BALL COVERS UNIROYAL CHEMICAL COMPANY, INC. (US) 2002-08-22 WO disclosed
US-20020049099-A1 Low cost, resilient, shear resistant polyurethane elastomers for golf ball covers UNIROYAL CHEMICAL COMPANY, INC. 2002-04-25 US disclosed
US-6309313-B1 AN INEXPENSIVE COVER OF A POLYETHERURETHANE COPOLYMER CHAIN EXTENDED BY A DIAMINE OR DIHYDROXY COMPOUND; POLYETHER MONOMER COMPRISING ETHYLENE GLYCOL OR ETHYLENE GLYCOL AND PROPYLENE GLYCOL; COLORFASTNESS; PHOTOSTABILITY UNIROYAL CHEMICAL COMPANY, INC. 2001-10-30 US disclosed
US-6174984-B1 Clear, resilient polyurethane elastomers UNIROYAL CHEMICAL COMPANY, INC. 2001-01-16 US disclosed
US-5041668-A Polyurethane Chain Extenders, Hardeners for Epoxy Resins ETHYL CORPORATION (US) 1991-08-20 US disclosed
US-5008453-A Sterically hindered chain extenders and curing agents for polyurethanes, polyureas, polyepoxides ETHYL CORPORATION (US) 1991-04-16 US disclosed
EP-0228190-B1 RIM POLYURETHANES COMPRISING MIXED DIAMINE CHAIN EXTENDERS AND PROCESS AND COMPOSITION FOR THEIR PRODUCTION ETHYL CORPORATION (US) 1991-02-27 EP disclosed
EP-0228190-A2 RIM polyurethanes comprising mixed diamine chain extenders and process and composition for their production ETHYL CORPORATION (US) 1987-07-08 EP disclosed
US-4631298-A REACTION INJECTION MOLDING POLYURETHANES ETHYL CORPORATION (US) 1986-12-23 US disclosed