Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779485 | 1.00 | DPP4 (0.47) | DPP4ACEFAPPREP | |
| SCHEMBL12343757 | 0.85 | ACE (0.46) | DPP4ACEFAPPREP | |
| SCHEMBL12343829 | 0.85 | ACE (0.46) | DPP4ACEFAPPREP | |
| SCHEMBL16656666 | 0.85 | ACE (0.46) | DPP4ACEFAPPREP | |
| SCHEMBL7364621 | 0.85 | ACE (0.62) | ACE | |
| SCHEMBL30874832 | 0.84 | DPP4 (0.46) | DPP4ACEFAPPREP | |
| SCHEMBL30493625 | 0.84 | DPP4 (0.60) | DPP4ACEFAPPREP | |
| SCHEMBL4330609 | 0.83 | FAP (0.41) | DPP4ACEFAPPREP | |
| SCHEMBL4327210 | 0.83 | FAP (0.41) | DPP4ACEFAPPREP | |
| SCHEMBL15129897 | 0.82 | DPP4 (0.51) | DPP4ACEFAPPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673385-B1 | MACROCYCLIC PEPTIDES ACTIVE AGAINST THE HEPATITIS C VIRUS | BOEHRINGER INGELHEIM INT (DE) | 2011-03-02 | — | — | EP | disclosed |