SCHEMBL30874832

SCHEMBL30874832

CNC(=O)NCC(=O)N1CCCC1C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 12/20 0.46
FAP Q12884 6/20 0.43
PREP P48147 6/20 0.43
ACE P12821 2/20 0.40
PPID Q08752 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8147714 0.86 FAP (0.45) DPP4FAPPREP
SCHEMBL12784268 0.86 FAP (0.45) DPP4FAPPREP
SCHEMBL30493625 0.85 DPP4 (0.60) DPP4FAPPREPACE
SCHEMBL12809058 0.84 DPP4 (0.47) DPP4FAPPREPACE
SCHEMBL21779485 0.84 DPP4 (0.47) DPP4FAPPREPACE
SCHEMBL15129897 0.83 DPP4 (0.51) DPP4FAPPREPACE
SCHEMBL19692655 0.83 DPP4 (0.51) DPP4FAPPREPACE
SCHEMBL12784948 0.83 EPHX2 (0.46) DPP4FAP
SCHEMBL18653084 0.82 DPP4 (0.49) DPP4FAPPREP
SCHEMBL17188719 0.82 DPP4 (0.47) DPP4FAPPREPACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117956985-A Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof 梅兹治疗公司 2024-04-30 CN disclosed