Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20224934 | 0.81 | GDA (0.38) | GDACYP3A4PMP22MAPK1LMNA | |
| SCHEMBL20224938 | 0.81 | GDA (0.38) | GDACYP3A4PMP22MAPK1LMNA | |
| SCHEMBL18519852 | 0.81 | PNP (0.45) | GDACYP3A4PMP22MAPK1LMNA | |
| SCHEMBL18510389 | 0.78 | SMN1; SMN2 (0.49) | CYP3A4RAB9AALDH1A1TSHRMEN1 | |
| SCHEMBL25080185 | 0.71 | KDM4E (0.40) | MAPK1LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL8043797 | 0.69 | GDA (0.36) | GDACYP3A4PMP22MAPK1LMNA | |
| SCHEMBL8259942 | 0.69 | RAB9A (0.42) | GDACYP3A4PMP22MAPK1RAB9A | |
| SCHEMBL9910656 | 0.68 | XDH (0.42) | GDACYP3A4PMP22MAPK1RAB9A | |
| SCHEMBL4560085 | 0.67 | GDA (0.53) | GDACYP3A4PMP22MAPK1LMNA | |
| SCHEMBL10998 | 0.67 | GDA (0.53) | GDACYP3A4PMP22MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907592-B1 | MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES | DAKO DENMARK AS (DK) | 2011-03-09 | — | — | EP | disclosed |