Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | IDE | P14735 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | HLCS | P50747 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21361159 | 0.89 | TDP1 (0.55) | TDP1PKMFOLH1F2PRSS1 | |
| SCHEMBL21361155 | 0.88 | TDP1 (0.49) | TDP1PKMFOLH1F2PRSS1 | |
| SCHEMBL21361156 | 0.85 | TDP1 (0.64) | TDP1PKMFOLH1F2PRSS1 | |
| SCHEMBL12809772 | 0.83 | FOLH1 (0.57) | TDP1PKMFOLH1F2PRSS1 | |
| SCHEMBL6972386 | 0.83 | FOLH1 (0.57) | TDP1PKMFOLH1F2PRSS1 | |
| SCHEMBL13485722 | 0.80 | FOLH1 (0.54) | TDP1PKMFOLH1F2PRSS1 | |
| SCHEMBL21361153 | 0.78 | TDP1 (0.62) | TDP1PKMFOLH1F2PRSS1 | |
| SCHEMBL20068708 | 0.76 | TDP1 (0.65) | TDP1PKMFOLH1F2PRSS1 | |
| SCHEMBL5903487 | 0.76 | TDP1 (0.65) | TDP1PKMFOLH1F2PRSS1 | |
| SCHEMBL21361160 | 0.76 | TDP1 (0.53) | TDP1PKMFOLH1F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10413621-B2 | Composition and methods for imaging cells | CASE WESTERN RESERVE UNIVERSITY (US) | 2019-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10413621-B2 | Composition and methods for imaging cells | MCL1, TP53, HNRNPAB | TDP1 3017/4885PKM 3706/4885FOLH1 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.