Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27642563 | 0.84 | PDE2A (0.50) | ALDH1A1HPGDEPHX2PDE2APOLB | |
| SCHEMBL9680427 | 0.83 | PTGS2 (0.50) | ALDH1A1EPHX2PDE2ACXCR2EPHX1 | |
| SCHEMBL9680432 | 0.83 | PTGS2 (0.50) | ALDH1A1EPHX2PDE2ACXCR2EPHX1 | |
| SCHEMBL10235461 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HPGDEPHX2PDE2APOLB | |
| SCHEMBL950460 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HPGDEPHX2PDE2APOLB | |
| SCHEMBL378939 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HPGDEPHX2PDE2APOLB | |
| SCHEMBL27181204 | 0.81 | EPHX1 (0.54) | ALDH1A1HPGDEPHX2PDE2ACXCR2 | |
| Hydrochloric Acid SCHEMBL3582167 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDEPHX2PDE2APOLB | |
| SCHEMBL4007061 | 0.80 | MEN1 (0.54) | HPGDMEN1KMT2ANPSR1ACACB | |
| SCHEMBL1822574 | 0.80 | CXCR2 (0.68) | HPGDKMT2ACXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917013-B1 | USE OF AZABICYCLO HEXANE DERIVATIVES | GLAXO GROUP LTD (GB) | 2011-03-09 | — | — | EP | disclosed |