SCHEMBL12810261

SCHEMBL12810261

CCn1c(=O)n(CC)c(=O)n(CCOC(=O)NCCO)c1=O

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.45
CHRNB2 P17787 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA4 P43681 1/20 0.43
GAA P10253 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GLA P06280 1/20 0.35
PLA2G4A P47712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13413672 0.92 CHRNB2 (0.45) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL13413692 0.89 CHRNB2 (0.43) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL13413693 0.89 CHRNB2 (0.43) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL16814928 0.83 ACHE (0.46) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL13413722 0.83 ACHE (0.45) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL13133661 0.83 CHRNB2 (0.43) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL13413689 0.82 APEX1 (0.44) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL13133663 0.82 ACHE (0.40) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL13413675 0.80 CREBBP (0.47) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL13413674 0.80 ACHE (0.42) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2165830-B1 Lithographic printing plate precursor and printing method using the same FUJIFILM CORP (JP) 2011-03-16 EP disclosed
US-20100071574-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20100071574-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed