Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746880 | 0.79 | MEN1 (0.32) | BRD4TSHR | |
| SCHEMBL2793920 | 0.78 | PTGER2 (0.35) | TSHR | |
| SCHEMBL6916806 | 0.78 | PTGER2 (0.35) | TSHR | |
| SCHEMBL10716754 | 0.77 | TSHR (0.34) | BRD4TSHR | |
| SCHEMBL10716749 | 0.77 | TSHR (0.34) | BRD4TSHR | |
| Methyl Cucurbate SCHEMBL2990000 | 0.76 | AKR1C4 (0.37) | — | |
| SCHEMBL11502808 | 0.76 | — | — | |
| Methyl Cucurbate SCHEMBL21400729 | 0.76 | AKR1C4 (0.37) | — | |
| Methyl Cucurbate SCHEMBL2795542 | 0.76 | AKR1C4 (0.37) | — | |
| SCHEMBL11742524 | 0.76 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298755-A1 | METHOD OF PRODUCING BICYCLO[3.1.0]HEXANE DERIVATIVE USING ENZYME | Taisho Pharmaceutical Co., Ltd. (JP) | 2011-03-23 | — | — | EP | disclosed |