Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716754 | 1.00 | TSHR (0.34) | TSHRBRD4GAAHSD17B10MGAM | |
| SCHEMBL11746880 | 0.87 | MEN1 (0.32) | TSHRBRD4 | |
| SCHEMBL11742524 | 0.83 | TSHR (0.31) | TSHR | |
| SCHEMBL18088607 | 0.78 | MEN1 (0.39) | TSHRBRD4GAAHSD17B10MGAM | |
| SCHEMBL17281763 | 0.78 | SLC6A12 (0.41) | — | |
| SCHEMBL1863234 | 0.77 | — | — | |
| SCHEMBL12810448 | 0.77 | BRD4 (0.32) | TSHRBRD4 | |
| SCHEMBL23963958 | 0.74 | CYP3A4 (0.35) | TSHRBRD4HSD17B10EPHX2 | |
| SCHEMBL8444550 | 0.73 | EPHX2 (0.44) | TSHRBRD4GAAHSD17B10MGAM | |
| SCHEMBL5638546 | 0.72 | TSHR (0.46) | TSHRBRD4GAAHSD17B10MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62026248-A | — | — | None | — | — | JP | disclosed |
| JP-S6226248-A | CIS-2-ALKYL-3-ALKOXYCARBONYLMETHYLCYCLOPENTANOL | T HASEGAWA CO LTD | 1987-02-04 | — | — | JP | disclosed |