Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Cucurbate SCHEMBL21400729 | 1.00 | AKR1C4 (0.37) | AKR1C4AKR1C3AKR1C2KDM4EALDH1A1 | |
| Methyl Cucurbate SCHEMBL2990000 | 1.00 | AKR1C4 (0.37) | AKR1C4AKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL21400807 | 0.85 | AKR1C4 (0.37) | AKR1C4AKR1C3AKR1C2OXER1CNR1 | |
| SCHEMBL21400840 | 0.84 | AKR1C4 (0.36) | AKR1C4AKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL6727788 | 0.83 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2ALDH1A1OXER1 | |
| SCHEMBL18853787 | 0.83 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2ALDH1A1OXER1 | |
| SCHEMBL30180824 | 0.83 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2ALDH1A1OXER1 | |
| SCHEMBL18853799 | 0.83 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2ALDH1A1OXER1 | |
| SCHEMBL669993 | 0.83 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2ALDH1A1OXER1 | |
| SCHEMBL29517213 | 0.83 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2ALDH1A1OXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2223680-B1 | Combination of monosaccharides and exfoliating agents and its cosmetic use | L'ORÉAL (FR) | 2017-10-18 | — | — | EP | claimed |
| US-20100168041-A1 | COMBINATION OF MONOSACCHARIDES AND DESQUAMATING AGENTS, AND USE THEREOF | L'OREAL (FR) | 2010-07-01 | — | — | US | claimed |
| US-20040029839-A1 | Compositions comprising jasmonic acid derivatives and use of these derivatives | L'OREAL S.A. (FR) | 2004-02-12 | — | — | US | claimed |
| US-20180213774-A1 | FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | BEDOUKIAN RESEARCH, INC. | 2018-08-02 | — | — | US | disclosed |
| WO-2016120574-A1 | HYDROSILANE/LEWIS ACID ADDUCT, PARTICULARLY ALUMINUM, IRON, AND ZINC, METHOD FOR PREPARING SAME, AND USE OF SAID SAME IN REACTIONS FOR REDUCING CARBONYL DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2016-08-04 | — | — | WO | disclosed |
| US-8603502-B2 | Compositions comprising jasmonic acid derivatives and use of these derivatives | L'OREAL S.A. (FR) | 2013-12-10 | — | — | US | disclosed |
| US-8481594-B2 | Compositions comprising jasmonic acid derivatives and use of these derivatives | L'OREAL S. A. (FR) | 2013-07-09 | — | — | US | disclosed |
| WO-2012117340-A1 | METHOD FOR THE COSMETIC TREATMENT OF SKIN REDNESS | L'OREAL (FR) | 2012-09-07 | — | — | WO | disclosed |
| US-20100179222-A1 | COMPOSITIONS COMPRISING JASMONIC ACID DERIVATIVES AND USE OF THESE DERIVATIVES | L'OREAL S.A. | 2010-07-15 | — | — | US | disclosed |
| US-20100168041-A1 | COMBINATION OF MONOSACCHARIDES AND DESQUAMATING AGENTS, AND USE THEREOF | L'OREAL (FR) | 2010-07-01 | — | — | US | disclosed |
| US-20100069497-A1 | COMPOSITIONS COMPRISING JASMONIC ACID DERIVATIVES AND USE OF THESE DERIVATIVES | L'OREAL | 2010-03-18 | — | — | US | disclosed |
| US-20040029839-A1 | Compositions comprising jasmonic acid derivatives and use of these derivatives | L'OREAL S.A. (FR) | 2004-02-12 | — | — | US | disclosed |
| US-4237308-A | BY DECARBOXYLATION IN THE PRESENCE OF SODIUM CHLORIDE | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1980-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069497-A1 | COMPOSITIONS COMPRISING JASMONIC ACID DERIVATIVES AND USE OF THESE DERIVATIVES | CBR1, CBR3, DECR1 | AKR1C4 48/4885AKR1C3 46/4885AKR1C2 132/4885 |
| US-20040029839-A1 | Compositions comprising jasmonic acid derivatives and use of these derivatives | CBR1, CBR3, DECR1 | AKR1C4 66/4885AKR1C3 35/4885AKR1C2 91/4885 |
| US-20100179222-A1 | COMPOSITIONS COMPRISING JASMONIC ACID DERIVATIVES AND USE OF THESE DERIVATIVES | CBR1, CBR3, DECR1 | AKR1C4 56/4885AKR1C3 48/4885AKR1C2 122/4885 |
| US-20100168041-A1 | COMBINATION OF MONOSACCHARIDES AND DESQUAMATING AGENTS, AND USE THEREOF | MAN2A1, MANBA, DPM1 | AKR1C4 3183/4885AKR1C3 3017/4885AKR1C2 2970/4885 |
| US-20180213774-A1 | FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | NOTUM, ACMSD, DDT | AKR1C4 1872/4885AKR1C3 1911/4885AKR1C2 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.